[HTML][HTML] Cell adhesion molecules in the pathogenesis of the schizophrenia

A Messina, C Crescimanno, G Cuccì, F Caraci… - Folia Medica, 2023 - foliamedica.bg
The causes of schizophrenia remain obscure and complex to identify. Alterations in
dopaminergic and serotonergic neurotransmission are, to date, the primary pharmacological …

When, Why and How to Re-challenge Clozapine in Schizophrenia Following Myocarditis

M Qubad, G Dupont, M Hahn, SS Martin, V Puntmann… - CNS drugs, 2024 - Springer
Clozapine-induced myocarditis (CIM) is among the most important adverse events limiting
the use of clozapine as the most effective treatment for schizophrenia. CIM necessitates the …

Longitudinal changes in DNA methylation associated with clozapine use in treatment-resistant schizophrenia from two international cohorts

AL Gillespie, EM Walker, E Hannon… - Translational …, 2024 - nature.com
The second-generation antipsychotic clozapine is used as a medication for treatment-
resistant schizophrenia. It has previously been associated with epigenetic changes in pre …

[HTML][HTML] Immunophenotyping schizophrenia subtypes stratified by antipsychotic response

Y Li, JWX Ong, YM See, JY Yee, C Tang… - Brain, Behavior, and …, 2025 - Elsevier
Immune dysfunction has been proposed to play a role in the pathophysiology behind the
development and persistence of psychosis. Current immunophenotyping studies are limited …

Mediation and longitudinal analysis to interpret the association between clozapine pharmacokinetics, pharmacogenomics, and absolute neutrophil count

SK Lock, SE Legge, DB Kappel, IR Willcocks… - Schizophrenia, 2023 - nature.com
Clozapine is effective at reducing symptoms of treatment-resistant schizophrenia, but it can
also induce several adverse outcomes including neutropenia and agranulocytosis. We used …

The Immunological interplay in Schizophrenia: Impact of Clozapine and Risperidone treatment-A randomized study

S Mehta, S Jaswal, A Sidana, G Kaur… - Annals of Psychaitry, 2024 - annalsofpsyj.com
Background: Recent research highlights the neuroimmunological basis of Schizophrenia
with an intrigue into biomarkers for Schizophrenia. Methods: It was a prospective …

[PDF][PDF] Immunoglobulin Levels in Schizophrenia and OCD during Rituximab Treatment

MB Humble, SS Stein, D Eklund, S Bejerot - oru.se
Background: Immunological/inflammatory mechanisms may be involved in the
pathophysiology, in schizophrenia (SCZ) as well as in obsessivecompulsive disorder (OCD) …