Recent progress in the oxidative bromination of arenes and heteroarenes

DB Jiang, FY Wu, HL Cui - Organic & Biomolecular Chemistry, 2023 - pubs.rsc.org
Oxidative bromination has been serving as a powerful tool for the synthesis of bromo-
containing molecules, as this bromination strategy features environmental friendliness, high …

Boron‐Mediated Regioselective Aromatic C−H Functionalization via an Aryl BF2 Complex

GH Shinde, H Sundén - Chemistry–A European Journal, 2023 - Wiley Online Library
An efficient regioselective functionalization of 2‐aryl‐heteroarenes and aryl aldehydes via
an azaaryl BF2 complex has been developed. Mechanistically the reaction comprises …

Regioselective ortho halogenation of N-aryl amides and ureas via oxidative halodeboronation: harnessing boron reactivity for efficient C–halogen bond installation

GH Shinde, GS Ghotekar, FMA Noa, L Öhrström… - Chemical …, 2023 - pubs.rsc.org
The installation of the C–halogen bond at the ortho position of N-aryl amides and ureas
represents a tool to prepare motifs that are ubiquitous in biologically active compounds. To …

Recent Update on Transition Metal‐Free C(sp2)−H Bond Halogenation in (Hetero) Arenes

S Mal, M Jana, S Sarkar - ChemistrySelect, 2021 - Wiley Online Library
Halogen incorporated arenes and heteroarenes are often used as useful intermediates as
well as target products in organic synthesis. Often, C− H bond halogenation is attempted …

Practical, mild and efficient electrophilic bromination of phenols by a new I (iii)-based reagent: The PIDA–AlBr 3 system

Y Satkar, V Ramadoss, PD Nahide, E García-Medina… - RSC …, 2018 - pubs.rsc.org
A practical electrophilic bromination procedure for phenols and phenol–ethers was
developed under efficient and very mild reaction conditions. A broad scope of arenes was …

Direct coupling of haloquinolines and sulfonyl chlorides leading to sulfonylated quinolines in water

P Bao, L Wang, Q Liu, D Yang, H Wang, X Zhao… - Tetrahedron …, 2019 - Elsevier
A simple and efficient method has been developed for construction of sulfonylated
quinolines via coupling of haloquinolines and sulfonyl chlorides in water. The present …

Combining Eosin Y with Selectfluor: A Regioselective Brominating System for Para-Bromination of Aniline Derivatives

B Huang, Y Zhao, C Yang, Y Gao, W Xia - Organic letters, 2017 - ACS Publications
A mild, metal-free, and absolutely para-selective bromination of aniline derivatives has been
developed in excellent yields, wherein the organic dye Eosin Y is employed as the bromine …

Amide-assisted radical strategy: Metal-free direct fluorination of arenes in aqueous media

D Liang, Y Li, S Gao, R Li, X Li, B Wang, H Yang - Green Chemistry, 2017 - pubs.rsc.org
A metal-and initiator-free direct fluorination of arenes with the assistance of an amide group
is developed. This reaction proceeded under simple aqueous conditions with good …

Electrochemical C–H Mono-/Multi-Bromination Regulation of N-Sulfonylanilines on a Cost-Effective Carbon Fiber Electrode and Its Prospective Electroactive …

S Xie, L Fu, Y Ding, Q Wang, C He, W Xu… - The Journal of …, 2024 - ACS Publications
Electrochemical C–H mono/multi-bromination regulation of N-sulfonylanilines on the cost-
effective CF electrode is described. This reaction proceeds smoothly under mild conditions …

Selectfluor-promoted regioselective chlorination/bromination of 2-aminopyridines and 2-aminodiazines using LiCl/LiBr

J Hu, G Zhou, Y Tian, X Zhao - Organic & Biomolecular Chemistry, 2019 - pubs.rsc.org
Using LiCl as a chlorine source, the chlorination of 2-aminopyridines or 2-aminodiazines in
the presence of Selectfluor and DMF is established under mild conditions. This method …