The processes behind drug loading and release in porous drug delivery systems

M Farzan, R Roth, J Schoelkopf, J Huwyler… - European Journal of …, 2023 - Elsevier
Porous materials are ubiquitous and exhibit properties suitable for depositing therapeutic
compounds. Drug loading in porous materials can protect the drug, control its release rate …

Design and pharmaceutical applications of porous particles

M Zhou, L Shen, X Lin, Y Hong, Y Feng - RSC advances, 2017 - pubs.rsc.org
Porous particles (PPs) are a novel kind of carrier with a large surface area, high porosity,
stable uniform porous structure, tunable pore sizes with narrow distribution, and well defined …

Porous hydroxyapatite for artificial bone applications

I Sopyan, M Mel, S Ramesh… - Science and Technology …, 2007 - iopscience.iop.org
Hydroxyapatite (HA) has been used clinically for many years. It has good biocompatibility in
bone contact as its chemical composition is similar to that of bone material. Porous HA …

Development, optimization, and characterization of solid self-nanoemulsifying drug delivery systems of valsartan using porous carriers

S Beg, S Swain, HP Singh, CN Patra, MEB Rao - Aaps Pharmscitech, 2012 - Springer
The present studies entail formulation development of novel solid self-nanoemulsifying drug
delivery systems (S-SNEDDS) of valsartan with improved oral bioavailability, and evaluation …

[HTML][HTML] Porous carriers for controlled/modulated drug delivery

G Ahuja, K Pathak - Indian journal of pharmaceutical sciences, 2009 - ncbi.nlm.nih.gov
Considerable research efforts have been directed in recent years towards the development
of porous carriers as controlled drug delivery matrices because of possessing several …

Carvedilol dissolution improvement by preparation of solid dispersions with porous silica

O Planinšek, B Kovačič, F Vrečer - International journal of pharmaceutics, 2011 - Elsevier
Impregnation of porous SiO2 (Sylysia) with carvedilol from acetone solution was used to
improve dissolution of this poorly water-soluble drug. Solvent evaporation in a vacuum …

Effect of a disintegration mechanism on wetting, water absorption, and disintegration time of orodispersible tablets

RM Pabari, Z Ramtoola - Journal of young pharmacists, 2012 - Elsevier
The aim ofthis study was to evaluate the influence of disintegration mechanism ofvarious
types of disintegrants on the absorption ratio (AR), Wetting time (WT), and disintegration time …

Ordered nanoporous silica as carriers for improved delivery of water insoluble drugs: a comparative study between three dimensional and two dimensional …

Y Wang, Q Zhao, Y Hu, L Sun, L Bai… - International journal of …, 2013 - Taylor & Francis
The goal of the present study was to compare the drug release properties and stability of the
nanoporous silica with different pore architectures as a matrix for improved delivery of poorly …

Composite particles based on particle engineering for direct compaction

Z Li, X Lin, L Shen, YL Hong, Y Feng - International journal of …, 2017 - Elsevier
Direct compaction (DC) is the preferred method for tablet production. However, only a
minority of the active pharmaceutical ingredients (APIs) can be truly manufactured into …

Improved absorption of meloxicam via salt formation with ethanolamines

HK Han, HK Choi - European Journal of Pharmaceutics and …, 2007 - Elsevier
The present study aimed to investigate the effect of ethanolamine salt formation on the
dissolution as well as in vivo pharmacokinetics of meloxicam. Three meloxicam …