Ancient herpes simplex 1 genomes reveal recent viral structure in Eurasia

M Guellil, L van Dorp, SA Inskip, JM Dittmar, L Saag… - Science …, 2022 - science.org
Human herpes simplex virus 1 (HSV-1), a life-long infection spread by oral contact, infects a
majority of adults globally. Phylogeographic clustering of sampled diversity into European …

Genetic history of Cambridgeshire before and after the Black Death

R Hui, CL Scheib, E D'Atanasio, SA Inskip… - Science …, 2024 - science.org
The extent of the devastation of the Black Death pandemic (1346–1353) on European
populations is known from documentary sources and its bacterial source illuminated by …

Ancient pathogens provide a window into health and well-being

CM Lewis Jr, MY Akinyi, SN DeWitte… - Proceedings of the …, 2023 - National Acad Sciences
This perspective draws on the record of ancient pathogen genomes and microbiomes
illuminating patterns of infectious disease over the course of the Holocene in order to …

Historical plague pandemics: perspectives from ancient DNA

E Gaul, MA Spyrou - Trends in Microbiology, 2024 - cell.com
Ancient DNA research has provided important insights into the evolutionary history of
Yersinia pestis during the historical plague pandemics. Future work should prioritise a more …

An 8000 years old genome reveals the Neolithic origin of the zoonosis Brucella melitensis

L L'hôte, I Light, V Mattiangeli, MD Teasdale… - Nature …, 2024 - nature.com
Brucella melitensis is a major livestock bacterial pathogen and zoonosis, causing disease
and infection-related abortions in small ruminants and humans. A considerable burden to …

Infectious disease in the Pleistocene: Old friends or old foes?

CJ Houldcroft, S Underdown - American Journal of Biological …, 2023 - Wiley Online Library
The impact of endemic and epidemic disease on humans has traditionally been seen as a
comparatively recent historical phenomenon associated with the Neolithisation of human …

A refined phylochronology of the second plague pandemic in Western Eurasia

M Keller, M Guellil, P Slavin, L Saag, K Irdt, H Niinemäe… - bioRxiv, 2023 - biorxiv.org
Although dozens of ancient Yersinia pestis genomes and a vast corpus of documentary data
are available, the origin and spread of consecutive outbreaks of the Second Plague …

Human Archaeological Dentin as Source of Polar and Less Polar Metabolites for Untargeted Metabolomic Research: The Case of Yersinia pestis

DA Badillo-Sanchez, DJL Jones, SA Inskip, CL Scheib - Metabolites, 2023 - mdpi.com
Metabolomic approaches, such as in clinical applications of living individuals, have shown
potential use for solving questions regarding the past when applied to archaeological …

Historic and prehistoric epidemics: an overview of sources available for the study of ancient pathogens

AC van der Kuyl - Epidemiologia, 2022 - mdpi.com
Since life on earth developed, parasitic microbes have thrived. Increases in host numbers, or
the conquest of a new species, provide an opportunity for such a pathogen to enjoy, before …

Establishment and Clinical Application of a RPA-LFS Assay for Detection of Capsulated and Non-Capsulated Haemophilus influenzae

Y Wang, A Liu, M Fu, J Guo, L Wang, X Zuo… - Frontiers in Cellular and …, 2022 - frontiersin.org
A recombinase polymerase amplification-lateral flow strip assay was established for
detection of the outer membrane protein P6 (omp6) and the capsule encoding gene bexA of …