[HTML][HTML] Thymoquinone: A novel strategy to combat cancer: A review

M Imran, A Rauf, IA Khan, M Shahbaz… - Biomedicine & …, 2018 - Elsevier
The higher consumption of fruit, herbs, spices, and vegetables is well known and practical
strategy to cure human cancers owing to their presence of bioactive compounds. Among …

Bax/Bcl-2 cascade is regulated by the EGFR pathway: therapeutic targeting of non-small cell lung cancer

M Alam, S Alam, A Shamsi, M Adnan… - Frontiers in …, 2022 - frontiersin.org
Non-small cell lung carcinoma (NSCLC) comprises 80%–85% of lung cancer cases. EGFR
is involved in several cancer developments, including NSCLC. The EGFR pathway …

Anti-cancer properties and mechanisms of action of thymoquinone, the major active ingredient of Nigella sativa

AF Majdalawieh, MW Fayyad… - Critical reviews in food …, 2017 - Taylor & Francis
Over the past two decades, studies have documented the wide-range anti-cancer effects of
Nigella sativa, known as black seed or black cumin. Thymoquinone (TQ), its major active …

[HTML][HTML] Anticancer activity of thymoquinone against breast cancer cells: Mechanisms of action and delivery approaches

H Shabani, MH Karami, J Kolour, Z Sayyahi… - Biomedicine & …, 2023 - Elsevier
The rising incidence of breast cancer has been a significant source of concern in the
medical community. Regarding the adverse effects and consequences of current treatments …

Potential anticancer properties and mechanisms of thymoquinone in osteosarcoma and bone metastasis

M Homayoonfal, Z Asemi, B Yousefi - Cellular & Molecular Biology Letters, 2022 - Springer
Despite great advances, therapeutic approaches of osteosarcoma, the most prevalent class
of preliminary pediatric bone tumors, as well as bone-related malignancies, continue to …

Therapeutic targeting of regulated signaling pathways of non-small cell lung carcinoma

GM Hasan, MI Hassan, SS Sohal, A Shamsi… - ACS omega, 2023 - ACS Publications
Non-small cell lung carcinoma (NSCLC) is the most common cancer globally.
Phytochemicals and small molecule inhibitors significantly prevent varying types of cancers …

Therapeutic implications of black seed and its constituent thymoquinone in the prevention of cancer through inactivation and activation of molecular pathways

AH Rahmani, MA Alzohairy, MA Khan… - Evidence‐Based …, 2014 - Wiley Online Library
The cancer is probably the most dreaded disease in both men and women and also major
health problem worldwide. Despite its high prevalence, the exact molecular mechanisms of …

Therapeutic implications and clinical manifestations of thymoquinone

M Alam, GM Hasan, MM Ansari, R Sharma, DK Yadav… - Phytochemistry, 2022 - Elsevier
Thymoquinone (TQ), a natural phytochemical predominantly found in Nigella sativa, has
been investigated for its numerous health benefits. TQ showed anti-cancer, anti-oxidant, and …

Nutritional Value and Preventive Role of Nigella sativa L. and Its Main Component Thymoquinone in Cancer: An Evidenced-Based Review of Preclinical and Clinical …

J Ansary, F Giampieri, TY Forbes-Hernandez, L Regolo… - Molecules, 2021 - mdpi.com
In recent times, scientific attention has been paid to different foods and their bioactive
components for the ability to inhibit the onset and progress of different types of cancer …

Enhanced efficacy and bioavailability of thymoquinone using nanoliposomal dosage form

MR Mohammadabadi, MR Mozafari - Journal of drug delivery science and …, 2018 - Elsevier
Thymoquinone (TQ) is the bioactive constituent of the volatile oil of different herbs and a
phytochemical constituent of Nigella sativa, cumin and some other herbs. It can modulate …