Abstract Aim The “2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure”
replaces the “2013 ACCF/AHA Guideline for the Management of Heart Failure” and the …

Abstract Machine learning (ML) is a sub-field of artificial intelligence that uses computer
algorithms to extract patterns from raw data, acquire knowledge without human input, and …

Background: Guidelines recommend that patients with heart failure with reduced ejection
fraction (HFrEF) have medical therapy titrated to target doses derived from clinical trials, as …

ABSTRACT Aim The “2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure”
replaces the “2013 ACCF/AHA Guideline for the Management of Heart Failure” and the …

Aims Concern about hypotension often leads to withholding of beneficial therapy in patients
with heart failure and reduced ejection fraction (HFrEF). We evaluated the efficacy and …

Importance Traditionally, physicians distinguished between mitral regurgitation (MR) as a
determinant of outcomes and MR as a biomarker of left-ventricular (LV) dysfunction by …

Background Although safety and tolerability of vericiguat were established in the VICTORIA
(Vericiguat Global Study in Subjects With Heart Failure With Reduced Ejection Fraction) trial …

Background For patients hospitalized for heart failure with reduced ejection fraction (HFrEF),
guidelines recommend optimization of medical therapy prior to discharge. The degree to …

Randomized controlled trials (RCTs) have established the efficacy of several therapies to
improve both symptoms and outcomes for patients with heart failure and reduced left …

Numerous guideline documents have issued recommendations to clinicians concerning the
treatment of chronic heart failure and a reduced ejection fraction. However, guidelines do …