European Resuscitation Council Guidelines 2021: cardiac arrest in special circumstances

C Lott, A Truhlář, A Alfonzo, A Barelli… - Resuscitation, 2021 - Elsevier
Abstract These European Resuscitation Council (ERC) Cardiac Arrest in Special
Circumstances guidelines are based on the 2020 International Consensus on …

Lipid emulsion to treat acute poisonings: mechanisms of action, indications, and controversies

K Jaffal, L Chevillard, B Mégarbane - Pharmaceutics, 2023 - mdpi.com
Biodetoxification using intravenous lipid emulsion (ILE) in acute poisoning is of growing
interest. As well as for local anesthetics, ILE is currently used to reverse toxicity caused by a …

[HTML][HTML] Applications of microbial organophosphate-degrading enzymes to detoxification of organophosphorous compounds for medical countermeasures against …

T Pashirova, R Salah-Tazdaït, D Tazdaït… - International Journal of …, 2024 - mdpi.com
Mining of organophosphorous (OPs)-degrading bacterial enzymes in collections of known
bacterial strains and in natural biotopes are important research fields that lead to the …

Spatiotemporally targeted polypeptide nanoantidotes improve chemotherapy tolerance of cisplatin

J Yang, T Su, H Zou, G Yang, J Ding… - Angewandte …, 2022 - Wiley Online Library
The toxicity of drugs causes various adverse effects in patients. While antidotes that
neutralize drug toxicity help reduce systemic damage during clinical therapy, these antidotes …

Porous polymers as universal reversal agents for heparin anticoagulants through an inclusion–sequestration mechanism

F Lin, SB Yu, YY Liu, CZ Liu, S Lu, J Cao… - Advanced …, 2022 - Wiley Online Library
Heparins are widely used anticoagulants for surgical procedures and extracorporeal
therapies. However, all of them have bleeding risks. Protamine sulfate, the only clinically …

Cell-membrane-cloaked oil nanosponges enable dual-modal detoxification

Y Chen, Y Zhang, J Zhuang, JH Lee, L Wang… - Acs Nano, 2019 - ACS Publications
The lack of pharmaceutical antidotes for deadly toxicants has motivated tremendous
research interests in seeking synthetic nanoscavengers to absorb and neutralize harmful …

Kreislaufstillstand unter besonderen Umständen

C Lott, A Truhlář, A Alfonzo, A Barelli… - Notfall+ …, 2021 - Springer
Zusammenfassung Diese Leitlinien des European Resuscitation Council (ERC) für den
Kreislaufstillstand unter besonderen Umständen basieren auf dem 2020 International …

Nanotherapeutics for Alleviating Anesthesia‐Associated Complications

B Lu, L Wei, G Shi, J Du - Advanced Science, 2024 - Wiley Online Library
Current management of anesthesia‐associated complications falls short in terms of both
efficacy and safety. Nanomaterials with versatile properties and unique nano‐bio …

Enzyme Nanoreactor for In Vivo Detoxification of Organophosphates

T Pashirova, Z Shaihutdinova… - … Applied Materials & …, 2022 - ACS Publications
A nanoreactor containing an evolved mutant of Saccharolobus solfataricus
phosphotriesterase (L72C/Y97F/Y99F/W263V/I280T) as a catalytic bioscavenger was made …

Tuning the envelope structure of enzyme nanoreactors for in vivo detoxification of organophosphates

T Pashirova, Z Shaihutdinova, D Tatarinov… - International Journal of …, 2023 - mdpi.com
Encapsulated phosphotriesterase nanoreactors show their efficacy in the prophylaxis and
post-exposure treatment of poisoning by paraoxon. A new enzyme nanoreactor (E-nRs) …