Human ALDH comprise 19 subfamilies in which ALDH1A1, ALDH1A3, ALDH3A1,
ALDH5A1, ALDH7A1, and ALDH18A1 are implicated in CSC. Studies have shown that …

Exploring the relationship between various neurotransmitters and breast cancer cell growth
has revealed their likely centrality to improving breast cancer treatment. Neurotransmitters …

Simple Summary Aldehyde dehydrogenase 1A3 (ALDH1A3) is the primary cause of the high
ALDH activity associated with cancer stem cell (CSC) populations in multiple cancers and its …

Modern cancer chemotherapy originated in the 1940s, and since then, many
chemotherapeutic agents have been developed. However, most of these agents show …

Metastasis is one of the important biological features of malignant tumors and one of the
main factors responsible for poor prognosis. Although the widespread application of newer …

Background Gamma-aminobutyric acid (GABA) plays an important role in tumorigenesis and
progression. Despite this, the role of Reactome GABA receptor activation (RGRA) on gastric …

Cisplatin (cDDP) resistance is a matter of concern in triple-negative breast cancer
therapeutics. We measured the metabolic response of cDDP-sensitive (S) and-resistant (R) …

Aldehyde dehydrogenase 1A3 (ALDH1A3) is a cancer stem cell marker that promotes
metastasis. Triple‐negative breast cancer (TNBC) progression has been linked to ALDH1A3 …

Abstract GABA (Gamma-aminobutyric acid), a crucial neurotransmitter in the central nervous
system, has gained significant attention in recent years due to its extensive benefits for …

Triple‐negative breast cancer (TNBC) is a highly aggressive and metastatic malignancy with
poor treatment outcomes. The interaction between the tumor microenvironment (TME) and …