Adhesion-type heterotrimeric guanine nucleotide–binding protein (G protein)–coupled
receptors (Adhesion-GPCRs) comprise a class of widely distributed seven-transmembrane …

While a wide range of G protein‐coupled receptors (GPCR) have emerged as prime targets
for pharmacological intervention long ago, a distinct group of GPCR has only recently been …

Macromolecules gain access to the cytoplasm of eukaryotic cells using one of several ways
of which clathrin-dependent endocytosis is the most researched. Although the mechanism of …

Latrophilin, a neuronal “adhesion-G protein-coupled receptor”, is the major brain receptor for
α-latrotoxin, a black widow spider toxin which stimulates strong neuronal exocytosis in …

Latrophilins (LPHN) are part of a yet unexplored family of receptors comprising three
isoforms, LPHN1-3, and belonging to a unique branch of G protein-coupled receptors …

The findings of a recent study associate LPHN3, a member of the latrophilin family, with an
increased risk of developing attention deficit/hyperactivity disorder (ADHD), the most …

Pacemaking activity in substantia nigra dopaminergic neurons is generated by the
coordinated activity of a variety of distinct somatodendritic voltage-and calcium-gated ion …

For more than three decades, the venom of the black widow spider and its principal active
components, latrotoxins, have been used to induce release of neurotransmitters and …

Tetratricopeptide (TPR)-domain proteins are involved in various cellular processes. The
TPR domain is known to be responsible for interaction with other proteins commonly …

Поступление в цитоплазму эукариотических клеток макромолекул реализуется
несколькими способами, из которых наиболее хорошо изучен клатрин-зависимый …