[HTML][HTML] Unbox the black-box for the medical explainable AI via multi-modal and multi-centre data fusion: A mini-review, two showcases and beyond

G Yang, Q Ye, J Xia - Information Fusion, 2022 - Elsevier
Abstract Explainable Artificial Intelligence (XAI) is an emerging research topic of machine
learning aimed at unboxing how AI systems' black-box choices are made. This research field …

Multimodal data fusion for cancer biomarker discovery with deep learning

S Steyaert, M Pizurica, D Nagaraj… - Nature machine …, 2023 - nature.com
Technological advances have made it possible to study a patient from multiple angles with
high-dimensional, high-throughput multiscale biomedical data. In oncology, massive …

A roadmap for multi-omics data integration using deep learning

M Kang, E Ko, TB Mersha - Briefings in Bioinformatics, 2022 - academic.oup.com
High-throughput next-generation sequencing now makes it possible to generate a vast
amount of multi-omics data for various applications. These data have revolutionized …

Artificial intelligence in healthcare

KH Yu, AL Beam, IS Kohane - Nature biomedical engineering, 2018 - nature.com
Artificial intelligence (AI) is gradually changing medical practice. With recent progress in
digitized data acquisition, machine learning and computing infrastructure, AI applications …

Histopathology images predict multi-omics aberrations and prognoses in colorectal cancer patients

PC Tsai, TH Lee, KC Kuo, FY Su, TLM Lee… - Nature …, 2023 - nature.com
Histopathologic assessment is indispensable for diagnosing colorectal cancer (CRC).
However, manual evaluation of the diseased tissues under the microscope cannot reliably …

Integrative omics for health and disease

KJ Karczewski, MP Snyder - Nature Reviews Genetics, 2018 - nature.com
Advances in omics technologies—such as genomics, transcriptomics, proteomics and
metabolomics—have begun to enable personalized medicine at an extraordinarily detailed …

A review on explainable artificial intelligence for healthcare: why, how, and when?

S Bharati, MRH Mondal… - IEEE Transactions on …, 2023 - ieeexplore.ieee.org
Artificial intelligence (AI) models are increasingly finding applications in the field of
medicine. Concerns have been raised about the explainability of the decisions that are …

Predicting non-small cell lung cancer prognosis by fully automated microscopic pathology image features

KH Yu, C Zhang, GJ Berry, RB Altman, C Ré… - Nature …, 2016 - nature.com
Lung cancer is the most prevalent cancer worldwide, and histopathological assessment is
indispensable for its diagnosis. However, human evaluation of pathology slides cannot …

Framing the challenges of artificial intelligence in medicine

KH Yu, IS Kohane - BMJ quality & safety, 2019 - qualitysafety.bmj.com
On a clear January morning in Florida, a Tesla enthusiast and network entrepreneur was
driving his new Tesla Model S on US Highway 27A, returning from a family trip. He had …

Liquid biopsy as a tool for the diagnosis, treatment, and monitoring of breast cancer

AJA Freitas, RL Causin, MB Varuzza, S Calfa… - International journal of …, 2022 - mdpi.com
Breast cancer (BC) is a highly heterogeneous disease. The treatment of BC is complicated
owing to intratumoral complexity. Tissue biopsy and immunohistochemistry are the current …