Abstract Jones, Glenville, Stephen A. Strugnell, and Hector F. DeLuca. Current
Understanding of the Molecular Actions of Vitamin D. Physiol. Rev. 78: 1193–1231, 1998 …

Ionized calcium (Ca 2÷) is the most common signal transduction element in cells ranging
from bacteria to specialized neurons. Unlike many other second-messenger mo! ecules, Ca …

Apoptotic-cell removal is critical for development, tissue homeostasis, and resolution of
inflammation. Although many candidate systems exist, only phosphatidylserine has been …

Regulation of adipose cell mass is a critical homeostatic process in higher vertebrates. The
conversion of fibroblasts into cells of the adipose lineage is induced by expression of the …

Calreticulin is an ER (endoplasmic reticulum) luminal Ca2+-buffering chaperone. The
protein is involved in regulation of intracellular Ca2+ homoeostasis and ER Ca2+ capacity …

The biological action of androgens is mediated through the androgen receptor (AR).
Androgen-bound AR functions as a transcription factor to regulate genes involved in an …

The endoplasmic reticulum (ER) plays a critical role in the synthesis and chaperoning of
membrane-associated and secreted proteins. The membrane is also an important site of …

Alternative splicing of the human glucocorticoid receptor (hGR) pre-mRNA generates two
highly homologous isoforms, termed hGR alpha and hGR beta. hGR alpha is a ligand …

Calreticulin is a ubiquitous Ca2+ binding protein, located in the endoplasmic reticulum
lumen, which has been implicated in many diverse functions including: regulation of …

Alternative splicing of the human glucocorticoid receptor gene generates a nonhormone
binding splice variant (hGRβ) that differs from the wild-type receptor (hGRα) only at the …