Protocols for molecular modeling with Rosetta3 and RosettaScripts
Previously, we published an article providing an overview of the Rosetta suite of
biomacromolecular modeling software and a series of step-by-step tutorials [Kaufmann, KW …
biomacromolecular modeling software and a series of step-by-step tutorials [Kaufmann, KW …
Chemical shift-based methods in NMR structure determination
Chemical shifts are highly sensitive probes harnessed by NMR spectroscopists and
structural biologists as conformational parameters to characterize a range of biological …
structural biologists as conformational parameters to characterize a range of biological …
The structure of APOBEC1 and insights into its RNA and DNA substrate selectivity
AD Wolfe, S Li, C Goedderz, XS Chen - NAR cancer, 2020 - academic.oup.com
Abstract APOBEC1 (APO1), a member of AID/APOBEC nucleic acid cytosine deaminase
family, can edit apolipoprotein B mRNA to regulate cholesterol metabolism. This APO1 RNA …
family, can edit apolipoprotein B mRNA to regulate cholesterol metabolism. This APO1 RNA …
Computational prediction of the heterodimeric and higher-order structure of gpE1/gpE2 envelope glycoproteins encoded by hepatitis C virus
H Freedman, MR Logan, D Hockman… - Journal of …, 2017 - Am Soc Microbiol
Despite the recent success of newly developed direct-acting antivirals against hepatitis C,
the disease continues to be a global health threat due to the lack of diagnosis of most …
the disease continues to be a global health threat due to the lack of diagnosis of most …
Cs-rosetta
S Nerli, NG Sgourakis - Methods in enzymology, 2019 - Elsevier
Abstract Chemical Shift-Rosetta (CS-Rosetta) is an automated method that employs NMR
chemical shifts to model protein structures de novo. In this chapter, we introduce the …
chemical shifts to model protein structures de novo. In this chapter, we introduce the …
Mapping the Ca2+ induced structural change in calreticulin
Calreticulin is a highly conserved multifunctional protein implicated in many different
biological systems and has therefore been the subject of intensive research. It is primarily …
biological systems and has therefore been the subject of intensive research. It is primarily …
Modeling of membrane proteins
D Latek, B Trzaskowski, S Niewieczerzał… - … Methods to Study the …, 2019 - Springer
The membrane proteins are still the “Wild West” of structural biology. Although more and
more membrane proteins structures are determined, their functioning is still difficult to …
more membrane proteins structures are determined, their functioning is still difficult to …
Organization of ATP-gated P2X1 receptor intracellular termini in apo and desensitized states
The human P2X1 receptor (hP2X1R) is a trimeric ligand-gated ion channel opened by
extracellular ATP. The intracellular amino and carboxyl termini play significant roles in …
extracellular ATP. The intracellular amino and carboxyl termini play significant roles in …
Introduction to the Rosetta special collection
SD Khare, TA Whitehead - Plos one, 2015 - journals.plos.org
The Rosetta macromolecular modeling software is a versatile, rapidly developing set of tools
that are now being routinely utilized to address state-of-the-art research challenges in …
that are now being routinely utilized to address state-of-the-art research challenges in …
Rosetta Broker for membrane protein structure prediction: concentrative nucleoside transporter 3 and corticotropin-releasing factor receptor 1 test cases
D Latek - BMC structural biology, 2017 - Springer
Background Membrane proteins are difficult targets for structure prediction due to the limited
structural data deposited in Protein Data Bank. Most computational methods for membrane …
structural data deposited in Protein Data Bank. Most computational methods for membrane …