Recent years have brought notable progress in the field of IgA nephropathy. Here, we
highlight important new directions and latest developments, including successful discovery …

OBJECTIVE: To evaluate whether vitamin D levels are related to the risk of developing
autoimmune diseases and whether supplementation with vitamin D can modify the course of …

Background There is a striking latitudinal gradient in multiple sclerosis (MS) prevalence, but
exceptions in Mediterranean Europe and northern Scandinavia, and some systematic …

Objectives To estimate the incidence and prevalence of multiple sclerosis (MS) by age and
describe secular trends and geographic variations within the UK over the 20-year period …

Objectives Previous studies have demonstrated a strong latitudinal gradient in multiple
sclerosis (MS) prevalence. Herein, we present a meta-analysis of the latitudinal gradient of …

IgA nephropathy (IgAN), major cause of kidney failure worldwide, is common in Asians,
moderately prevalent in Europeans, and rare in Africans. It is not known if these differences …

Background Multiple sclerosis (MS) appears to develop in genetically susceptible
individuals as a result of environmental exposures. Epstein-Barr virus (EBV) infection is an …

Background Multiple sclerosis (MS) is a leading cause of disability in young adults.
Susceptibility to MS is determined by environmental exposure on the background of genetic …

OBJECTIVES:: We evaluated the epidemiologic evidence that vitamin D may be related to
human autoimmune disease risk. METHODS:: PubMed, limited to English from inception …

G protein–coupled receptors (GPCRs) play critical roles in regulating processes such as
cellular homeostasis, responses to stimuli, and cell signaling. Accordingly, GPCRs have …