Thrombus composition and efficacy of thrombolysis and thrombectomy in acute ischemic stroke

P Jolugbo, RAS Ariëns - Stroke, 2021 - Am Heart Assoc
Thrombi retrieved from patients with acute ischemic stroke are highly heterogeneous.
Recent data suggest that thrombus composition may impact on mechanical thrombectomy …

Thrombus structural composition in cardiovascular disease

G Alkarithi, C Duval, Y Shi, FL Macrae… - … , and vascular biology, 2021 - Am Heart Assoc
Thrombosis is a major complication of cardiovascular disease, leading to myocardial
infarction, acute ischemic stroke, or venous thromboembolism. Thrombosis occurs when a …

Degradable gelatin-based IPN cryogel hemostat for rapidly stopping deep noncompressible hemorrhage and simultaneously improving wound healing

Y Huang, X Zhao, Z Zhang, Y Liang, Z Yin… - Chemistry of …, 2020 - ACS Publications
Biodegradable cryogel wound dressing which can stop deep noncompressible hemorrhage
and simultaneously promote wound healing is a highly promising biomaterial in clinics …

Injectable antibacterial conductive nanocomposite cryogels with rapid shape recovery for noncompressible hemorrhage and wound healing

X Zhao, B Guo, H Wu, Y Liang, PX Ma - Nature communications, 2018 - nature.com
Developing injectable antibacterial and conductive shape memory hemostatic with high
blood absorption and fast recovery for irregularly shaped and noncompressible hemorrhage …

Snake extract–laden hemostatic bioadhesive gel cross-linked by visible light

Y Guo, Y Wang, X Zhao, X Li, Q Wang, W Zhong… - Science …, 2021 - science.org
Bioadhesives reduce operation time and surgical complications. However, in the presence
of blood, adhesion strength is often compromised. Inspired by the blood clotting activity of …

Injectable Self‐Expanding/Self‐Propelling Hydrogel Adhesive with Procoagulant Activity and Rapid Gelation for Lethal Massive Hemorrhage Management

X Zhao, Y Huang, Z Li, J Chen, J Luo, L Bai… - Advanced …, 2024 - Wiley Online Library
Developing hydrogels that can quickly reach deep bleeding sites, adhere to wounds, and
expand to stop lethal and/or noncompressible bleeding in civil and battlefield environments …

Fibrin formation, structure and properties

JW Weisel, RI Litvinov - Fibrous proteins: structures and mechanisms, 2017 - Springer
Fibrinogen and fibrin are essential for hemostasis and are major factors in thrombosis,
wound healing, and several other biological functions and pathological conditions. The X …

Injectable dry cryogels with excellent blood-sucking expansion and blood clotting to cease hemorrhage for lethal deep-wounds, coagulopathy and tissue regeneration

X Zhao, Y Liang, B Guo, Z Yin, D Zhu, Y Han - Chemical Engineering …, 2021 - Elsevier
Designing expandable dry cryogels with biodegradability, rapid blood-sucking expansion
and hemostasis for lethal non-compressible hemorrhage and coagulopathy hemorrhage still …

Superporous sponge prepared by secondary network compaction with enhanced permeability and mechanical properties for non-compressible hemostasis in pigs

T Jiang, S Chen, J Xu, Y Zhang, H Fu, Q Ling… - Nature …, 2024 - nature.com
Developing superporous hemostatic sponges with simultaneously enhanced permeability
and mechanical properties remains challenging but highly desirable to achieve rapid …

Thrombosis and platelets: an update

M Koupenova, BE Kehrel, HA Corkrey… - European heart …, 2017 - academic.oup.com
Haemostasis and thrombosis are complex, multifactorial processes. There is an evolving
understanding of the mechanisms influencing vascular occlusion and the role of …