Bile acids (BAs) are cholesterol-derived metabolites that facilitate the intestinal absorption
and transport of dietary lipids. Recently, BAs also emerged as pivotal signaling molecules …

Bile acids (BAs) are amphiphilic molecules with 24 carbon atoms and consist of a
hydrophobic and a rigid steroid nucleus, to which are attached a hydrophilic hydroxyl group …

Diabetes (both type-1 and type-2) affects millions of individuals worldwide. A major cause of
death for individuals with diabetes is cardiovascular diseases, in part since both types of …

Mitochondria have diverse functions critical to whole-body metabolic homeostasis.
Endurance training alters mitochondrial activity, but systematic characterization of these …

Background Globally, type 2 diabetes has continued to increase, now accounting for over
90% of all diabetes cases. Though the magnitude of uncontrolled glycaemic levels in …

We propose a mechanistic model for the development of diabetic myopathy based on the
human findings to date. This model suggests that repeated insulin injections in those with …

Metabolic syndrome is a key risk factor and co-morbidity in multiple sclerosis (MS) and other
neurological conditions, such that a better understanding of how a high fat diet contributes to …

Abstract Purpose of Review Metabolomics enables rapid interrogation of widespread
metabolic processes making it well suited for studying diabetes. Here, we review the current …

Multi-omic data and genome-scale microbial metabolic models have allowed us to examine
microbial communities, community function, and interactions in ways that were not available …

Context Previous investigations on skeletal muscle health in type 1 diabetes (T1D) have
generally focused on later stages of disease progression where comorbidities are present …