Immunometabolism at the heart of cardiovascular disease

M DeBerge, R Chaudhary, S Schroth… - Basic to Translational …, 2023 - jacc.org
Immune cell function among the myocardium, now more than ever, is appreciated to
regulate cardiac function and pathophysiology. This is the case for both innate immunity …

Genomic, proteomic, and metabolic comparisons of small animal models of heart failure with preserved ejection fraction: a tale of mice, rats, and cats

AN Smith, R Altara, G Amin, NJ Habeichi… - Journal of the …, 2022 - Am Heart Assoc
Heart failure with preserved ejection fraction (HFpEF) remains a medical anomaly that
baffles researchers and physicians alike. The overall phenotypical changes of diastolic …

Towards metabolomic-based precision approaches for classifying and treating heart failure

VS Hahn, S Selvaraj, K Sharma, SH Shah - Basic to Translational Science, 2024 - jacc.org
Both heart failure and cardiometabolic disease are on the rise, and abnormal cardiac and
peripheral metabolism are central to the syndrome of heart failure. Advances in metabolomic …

Metabolomic Association and Risk Prediction With Heart Failure in Older Adults

G Liu, NQH Nguyen, KE Wong, SK Agarwal… - Circulation: Heart …, 2024 - Am Heart Assoc
BACKGROUND: Older adults have markedly increased risks of heart failure (HF),
specifically HF with preserved ejection fraction (HFpEF). Identifying novel biomarkers can …

Changes in human sweat metabolome conditioned by severity of obstructive sleep apnea and intermittent hypoxemia

LS Castillo‐Peinado… - Journal of Sleep …, 2024 - Wiley Online Library
Obstructive sleep apnea (OSA) is a sleep disorder that has been associated with the
incidence of other pathologies. Diagnosis is mainly based on the apnea–hypopnea index …