The geometry of domain-general performance monitoring in the human medial frontal cortex

Z Fu, D Beam, JM Chung, CM Reed, AN Mamelak… - Science, 2022 - science.org
Controlling behavior to flexibly achieve desired goals depends on the ability to monitor one's
own performance. It is unknown how performance monitoring can be both flexible, to support …

Cortical microcircuitry of performance monitoring

A Sajad, DC Godlove, JD Schall - Nature Neuroscience, 2019 - nature.com
The medial frontal cortex enables performance monitoring, indexed by the error-related
negativity (ERN) and manifested by performance adaptations. We recorded …

Static and dynamic coding in distinct cell types during associative learning in the prefrontal cortex

F Ceccarelli, L Ferrucci, F Londei, S Ramawat… - Nature …, 2023 - nature.com
The prefrontal cortex maintains information in memory through static or dynamic population
codes depending on task demands, but whether the population coding schemes used are …

Interneuron-specific gamma synchronization indexes cue uncertainty and prediction errors in lateral prefrontal and anterior cingulate cortex

K Banaie Boroujeni, P Tiesinga, T Womelsdorf - Elife, 2021 - elifesciences.org
Inhibitory interneurons are believed to realize critical gating functions in cortical circuits, but
it has been difficult to ascertain the content of gated information for well-characterized …

Layer-specific pyramidal neuron properties underlie diverse anterior cingulate cortical motor and limbic networks

M Medalla, W Chang, S Ibañez… - Cerebral …, 2022 - academic.oup.com
The laminar cellular and circuit mechanisms by which the anterior cingulate cortex (ACC)
exerts flexible control of motor and affective information for goal-directed behavior have not …

Muscarinic acetylcholine receptor localization on distinct excitatory and inhibitory neurons within the ACC and LPFC of the rhesus monkey

A Tsolias, M Medalla - Frontiers in Neural Circuits, 2022 - frontiersin.org
Acetylcholine (ACh) can act on pre-and post-synaptic muscarinic receptors (mAChR) in the
cortex to influence a myriad of cognitive processes. Two functionally-distinct regions of the …

[HTML][HTML] Neurodevelopment of the incentive network facilitates motivated behaviour from adolescence to adulthood

D Willinger, II Karipidis, P Dimanova, S Walitza, S Brem - NeuroImage, 2021 - Elsevier
The ability to enhance motivated performance through incentives is crucial to guide and
ultimately optimise the outcome of goal-directed behaviour. It remains largely unclear how …

The midcingulate cortex and temporal integration

E Procyk, V Fontanier, M Sarazin, B Delord… - International Review of …, 2021 - Elsevier
The ability to integrate information across time at multiple timescales is a vital element of
adaptive behavior, because it provides the capacity to link events separated in time, extract …

Anterior Cingulate Cortex Causally Supports Meta-Learning

RL Treuting, KB Boroujeni, CG Gerrity, P Tiesinga… - bioRxiv, 2024 - biorxiv.org
In dynamic environments with volatile rewards the anterior cingulate cortex (ACC) is
believed to determine whether a visual object is relevant and should be chosen. The ACC …

Cell-type specific cholinergic modulation in anterior cingulate and lateral prefrontal cortices of the rhesus macaque

A Tsolias - 2023 - search.proquest.com
The lateral prefrontal cortex (LPFC) and the anterior cingulate cortex (ACC) are two key
regions of the frontal executive control network. Ascending cholinergic pathways …