[HTML][HTML] Long non-coding RNAs: definitions, functions, challenges and recommendations

JS Mattick, PP Amaral, P Carninci… - … reviews Molecular cell …, 2023 - nature.com
Genes specifying long non-coding RNAs (lncRNAs) occupy a large fraction of the genomes
of complex organisms. The term 'lncRNAs' encompasses RNA polymerase I (Pol I), Pol II …

[HTML][HTML] LncRNAs in breast cancer: a link to future approaches

N Sideris, P Dama, S Bayraktar, T Stiff… - Cancer gene …, 2022 - nature.com
Breast cancer affects millions of women each year. Despite recent advances in targeted
treatments breast cancer remains a significant threat to women's health. In recent years the …

Developmental dynamics of RNA translation in the human brain

EE Duffy, B Finander, GH Choi, AC Carter… - Nature …, 2022 - nature.com
The precise regulation of gene expression is fundamental to neurodevelopment, plasticity
and cognitive function. Although several studies have profiled transcription in the developing …

[图书][B] RNA, the epicenter of genetic information

J Mattick, P Amaral - 2023 - library.oapen.org
The origin story and emergence of molecular biology is muddled. The early triumphs in
bacterial genetics and the complexity of animal and plant genomes complicate an intricate …

[HTML][HTML] CHESS 3: an improved, comprehensive catalog of human genes and transcripts based on large-scale expression data, phylogenetic analysis, and protein …

A Varabyou, MJ Sommer, B Erdogdu, I Shinder… - Genome biology, 2023 - Springer
CHESS 3 represents an improved human gene catalog based on nearly 10,000 RNA-seq
experiments across 54 body sites. It significantly improves current genome annotation by …

Long noncoding RNA and protein abundance in lncRNPs

M Wu, LZ Yang, LL Chen - Rna, 2021 - rnajournal.cshlp.org
Although long noncoding RNAs (lncRNAs) are generally expressed at low levels, emerging
evidence has revealed that many play important roles in gene regulation by a variety of …

[HTML][HTML] Long non-coding RNAs: mechanisms, experimental, and computational approaches in identification, characterization, and their biomarker potential in cancer

A Chowdhary, V Satagopam, R Schneider - Frontiers in Genetics, 2021 - frontiersin.org
Long non-coding RNAs are diverse class of non-coding RNA molecules> 200 base pairs of
length having various functions like gene regulation, dosage compensation, epigenetic …

[HTML][HTML] A New Understanding of Long Non-Coding RNA in Hepatocellular Carcinoma—From m6A Modification to Blood Biomarkers

JW Eun, JY Cheong, JY Jeong, HS Kim - Cells, 2023 - mdpi.com
With recent advancements in biological research, long non-coding RNAs (lncRNAs) with
lengths exceeding 200 nucleotides have emerged as pivotal regulators of gene expression …

[HTML][HTML] MARS an improved de novo peptide candidate selection method for non-canonical antigen target discovery in cancer

H Liao, C Barra, Z Zhou, X Peng, I Woodhouse… - Nature …, 2024 - nature.com
Understanding the nature and extent of non-canonical human leukocyte antigen (HLA)
presentation in tumour cells is a priority for target antigen discovery for the development of …

[HTML][HTML] Rare variants in long non-coding RNAs are associated with blood lipid levels in the TOPMed whole-genome sequencing study

Y Wang, MS Selvaraj, X Li, Z Li, JA Holdcraft… - The American Journal of …, 2023 - cell.com
Long non-coding RNAs (lncRNAs) are known to perform important regulatory functions in
lipid metabolism. Large-scale whole-genome sequencing (WGS) studies and new statistical …