Correlates of protection against SARS‐CoV‐2 infection and COVID‐19 disease

D Goldblatt, G Alter, S Crotty… - Immunological reviews, 2022 - Wiley Online Library
Antibodies against epitopes in S1 give the most accurate CoP against infection by the SARS‐
CoV‐2 coronavirus. Measurement of those antibodies by neutralization or binding assays …

Why does the severity of COVID-19 differ with age?: understanding the mechanisms underlying the age gradient in outcome following SARS-CoV-2 infection

P Zimmermann, N Curtis - The Pediatric Infectious Disease …, 2022 - journals.lww.com
Although there are many hypotheses for the age-related difference in the severity of COVID-
19, differences in innate, adaptive and heterologous immunity, together with differences in …

Persistent B cell memory after SARS-CoV-2 vaccination is functional during breakthrough infections

S Terreri, EP Mortari, MR Vinci, C Russo, C Alteri… - Cell host & …, 2022 - cell.com
Breakthrough SARS-CoV-2 infections in fully vaccinated individuals are considered a
consequence of waning immunity. Serum antibodies represent the most measurable …

The molecular mechanism of SARS-CoV-2 evading host antiviral innate immunity

W Gu, H Gan, Y Ma, L Xu, ZJ Cheng, B Li, X Zhang… - Virology journal, 2022 - Springer
Abstract The newly identified Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-
CoV-2) has resulted in a global health emergency (COVID-19) because of its rapid spread …

Assessment of sequelae of COVID-19 nearly 1 year after diagnosis

F Zhou, M Tao, L Shang, Y Liu, G Pan, Y Jin… - Frontiers in …, 2021 - frontiersin.org
Background: A previous study has shown that 81% of the COVID-19 patients had mild or
moderate symptoms. However, most studies on the sequelae in COVID-19 patients focused …

SARS-CoV-2 vaccine induced atypical immune responses in antibody defects: everybody does their best

AF Salinas, EP Mortari, S Terreri, C Quintarelli… - Journal of clinical …, 2021 - Springer
Background Data on immune responses to SARS-CoV-2 in patients with Primary Antibody
Deficiencies (PAD) are limited to infected patients and to heterogeneous cohorts after …

IgA antibodies and IgA deficiency in SARS-CoV-2 infection

I Quinti, EP Mortari, A Fernandez Salinas… - Frontiers in Cellular …, 2021 - frontiersin.org
A large repertoire of IgA is produced by B lymphocytes with T-independent and T-dependent
mechanisms useful in defense against pathogenic microorganisms and to reduce immune …

Highly specific memory B cells generation after the 2nd dose of BNT162b2 vaccine compensate for the decline of serum antibodies and absence of mucosal IgA

E Piano Mortari, C Russo, MR Vinci, S Terreri… - Cells, 2021 - mdpi.com
Specific memory B cells and antibodies are a reliable read-out of vaccine efficacy. We
analysed these biomarkers after one and two doses of BNT162b2 vaccine. The second dose …

[HTML][HTML] Asymptomatic and symptomatic SARS-CoV-2 infections elicit polyfunctional antibodies

J Dufloo, L Grzelak, I Staropoli, Y Madec, L Tondeur… - Cell Reports …, 2021 - cell.com
Summary Many SARS-CoV-2-infected individuals remain asymptomatic. Little is known
about the extent and quality of their antiviral humoral response. Here, we analyze antibody …

Kinetics of the B-and T-cell immune responses after 6 months from SARS-CoV-2 mRNA vaccination in patients with rheumatoid arthritis

C Farroni, A Picchianti-Diamanti, A Aiello… - Frontiers in …, 2022 - frontiersin.org
Objective To assess the kinetics of the humoral and cell-mediated responses after severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination in rheumatoid arthritis …