Muscles and bones are intricately connected tissues displaying marked co-variation during
development, growth, aging, and in many diseases. While the diagnosis and treatment of …

In recent decades, the mechanism underlying bone metabolic disorders based on energy
metabolism has been heavily researched. Bone resorption by osteoclasts plays an important …

Glucocorticoids are effective immunomodulatory drugs used for many inflammatory
disorders as well as in transplant recipients. However, both iatrogenic and endogenous …

Osteoporosis, a metabolic bone disease characterized by low bone mineral density and
deterioration of bone microarchitecture, has led to a high risk of fatal osteoporotic fractures …

The gut microbiome is a collection of microorganisms and parasites in the gastrointestinal
tract. Many factors can affect this community's composition, such as age, sex, diet …

Cushing's syndrome is defined by prolonged exposure to glucocorticoids, leading to excess
morbidity and mortality. Diagnosis of this rare pathology is difficult due to the low specificity …

Osteoporosis is a systemic condition of the skeleton that leads to diminished bone mass, a
breakdown in the bone tissue's microscopic architecture, and an elevated risk of breaking a …

Pivotal in many ways for human health, the control of adult bone mass is governed by
complex, incompletely understood crosstalk namely between mesenchymal stem cells …

Purpose To explore the molecular mechanism of luteolin in the treatment of osteoporosis
(OP) by network pharmacological prediction and experimentation. Methods The target …

Osteoporosis is a kind of bone diseases characterized by dynamic imbalance of bone
formation and bone absorption, which is prone to fracture, and seriously endangers human …