Transcriptomics for clinical and experimental biology research: hang on a seq

T Stokes, HH Cen, P Kapranov, IJ Gallagher… - Advanced …, 2023 - Wiley Online Library
Sequencing the human genome empowers translational medicine, facilitating transcriptome‐
wide molecular diagnosis, pathway biology, and drug repositioning. Initially, microarrays are …

Single-Cell Sequencing Technology and Its Application in the Study of Central Nervous System Diseases

Y Ding, YY Peng, S Li, C Tang, J Gao, HY Wang… - Cell Biochemistry and …, 2024 - Springer
The mammalian central nervous system consists of a large number of cells, which contain
not only different types of neurons, but also a large number of glial cells, such as astrocytes …

Transcriptome analysis reveals the peptide toxins diversity of Macrothele palpator venom

X Xiao, X Luo, C Huang, X Feng, M Wu, M Lu… - International journal of …, 2023 - Elsevier
Spider venom is a large pharmacological repertoire of different bioactive peptide toxins.
However, obtaining crude venom from some spiders is challenging. Thus, studying …

Stem Lodging Resistance-1 controls stem strength by positively regulating the biosynthesis of cell wall components in Capsicum annuum L.

Q Li, C Fu, B Yang, H Yu, H He, Q Xu… - Horticulture …, 2024 - academic.oup.com
Lodging presents a significant challenge in cultivating high-yield crops with extensive above-
ground biomass, yet the molecular mechanisms underlying this phenomenon in the …

Lysine 2‐hydroxyisobutyrylation proteomics analyses reveal the regulatory mechanism of Ca MYB61‐CaAFR1 module in regulating stem development in Capsicum …

Q Li, C Fu, B Hu, B Yang, H Yu, H He, Q Xu… - The Plant …, 2024 - Wiley Online Library
Plant stems constitute the most abundant renewable resource on earth. The function of
lysine (K)‐2‐hydroxyisobutyrylation (Khib), a novel post‐translational modification (PTM) …

Gene Expression Analysis in gla-Mutant Zebrafish Reveals Enhanced Ca2+ Signaling Similar to Fabry Disease

HOA Elsaid, H Tjeldnes, M Rivedal, C Serre… - International Journal of …, 2022 - mdpi.com
Fabry disease (FD) is an X-linked inborn metabolic disorder due to partial or complete
lysosomal α-galactosidase A deficiency. FD is characterized by progressive renal …

reanalyzerGSE: tackling the everlasting lack of reproducibility and reanalyses in transcriptomics

JL Ruiz, LC Terrón-Camero, J Castillo-González… - bioRxiv, 2023 - biorxiv.org
In the current context of transcriptomics democratization, there is an unprecedented surge in
the number of studies and datasets. However, advances are hampered by aspects such as …

Transcriptome software results show significant variation among different commercial pipelines

CN Thawng, GB Smith - BMC genomics, 2023 - Springer
Background We have been documenting the biological responses to low levels of radiation
(natural background) and very low level radiation (below background), and thus these …

Evolutionary characterization and pathogenicity of Getah virus from pigs in Guangdong Province of China

J Pan, H Zhang, X Chen, M Zeng, H Han, Y Guo, J Li… - Archives of …, 2023 - Springer
Getah virus (GETV) is an emerging zoonotic virus that can infect humans and many
mammals through mosquitoes. In this study, a novel pathogenic GETV strain, GDQY2022 …

[HTML][HTML] Identification Drug Targets for Oxaliplatin-Induced Cardiotoxicity without Affecting Cancer Treatment through Inter Variability Cross-Correlation Analysis …

J Du, LC Sudlow, H Biswas, JD Mitchell, S Mollah… - bioRxiv, 2024 - ncbi.nlm.nih.gov
The successful treatment of side effects of chemotherapy faces two major limitations: the
need to avoid interfering with pathways essential for the cancer-destroying effects of the …