The number of publicly available parasitic worm genome sequences has increased
dramatically in the past three years, and research interest in helminth functional genomics is …

Hookworms are soil-transmitted nematode parasites that can reside for many years in the
small intestine of their human hosts; Necator americanus is the predominant infecting …

Parasitic nematodes (roundworms) and platyhelminths (flatworms) cause debilitating
chronic infections of humans and animals, decimate crop production and are a major …

Helminths have evolved to become experts at subverting immune surveillance. Through
potent and persistent immune tempering, helminths can remain undetected in human …

Soil-transmitted nematodes, including the Strongyloides genus, cause one of the most
prevalent neglected tropical diseases. Here we compare the genomes of four Strongyloides …

Helminth parasites defy immune exclusion through sophisticated evasion mechanisms,
including activation of host immunosuppressive regulatory T (Treg) cells. The mouse …

Haemonchus contortus is a globally distributed and economically important gastrointestinal
pathogen of small ruminants and has become a key nematode model for studying …

Animals found in close proximity to humans in low-and middle-income countries (LMICs)
harbor many pathogens capable of infecting humans, transmissible via their feces. Contact …

The major soil-transmitted helminths that infect humans are the roundworms, whipworms
and hookworms. Soil-transmitted helminth infections rank among the most important …

Helminth parasites are a highly successful group of pathogens that challenge the immune
system in a manner distinct from rapidly replicating infectious agents. Of this group …