Ovarian aging is a natural and physiological aging process characterized by loss of quantity
and quality of oocyte or follicular pool. As it is generally accepted that women are born with a …

Reproductive disorders, including intrauterine adhesion (IUA), premature ovarian
insufficiency (POI), and polycystic ovary syndrome (PCOS), are great threats to female …

Ovarian aging leads to menopause, loss of fertility and other disorders in multiple organs,
which brings great distress to women. For ethical reasons, it is impossible to use humans as …

Despite advancements in assisted reproductive technology (ART), achieving successful
pregnancy rates remains challenging. Diminished ovarian reserve and premature ovarian …

Female reproductive aging is, in a way, a biological phenomenon that develops along
canonical molecular pathways; however, it has particular features. Recent studies revealed …

The post-reproductive phase or menopause in females is triggered by a physiological timer
that depends on a threshold of follicle number in the ovary. Curiously, reproductive …

Oxidative stress dysfunction has recently been found to be involved in the pathogenesis of
premature ovarian insufficiency (POI). Previously, we found that advanced oxidation protein …

Premature ovarian insufficiency (POI) is a clinically heterogeneous disease that may
seriously affect the physical and mental health of women of reproductive age. POI primarily …

Objective To study the diagnostic yield, including variants in genes yet to be incriminated, of
whole exome sequencing (WES) in familial cases of premature ovarian insufficiency (POI) …

Background: Despite distinct underlying aetiologies, the clinical phenotypes and hormonal
profiles of children with various differences of sex development (DSD) are often similar …