Recent progress and prospects for anti-cytokine therapy in preclinical and clinical acute lung injury

GP Fadanni, JB Calixto - Cytokine & Growth Factor Reviews, 2023 - Elsevier
Acute respiratory distress syndrome (ARDS) is a heterogeneous cause of respiratory failure
that has a rapid onset, a high mortality rate, and for which there is no effective …

A comprehensive review on the efficacy of several pharmacologic agents for the treatment of COVID-19

F Haddad, G Dokmak, R Karaman - Life, 2022 - mdpi.com
Simple Summary Treatments for coronavirus disease-2019 (COVID-19) have utilized a
variety of medications, including antivirals, immunomodulators, and other therapeutics such …

[HTML][HTML] Liver injury in COVID-19: Clinical features, potential mechanisms, risk factors and clinical treatments

SW Zhao, YM Li, YL Li, C Su - World Journal of Gastroenterology, 2023 - ncbi.nlm.nih.gov
Abstract The coronavirus disease 2019 (COVID-19) pandemic has been a serious threat to
global health for nearly 3 years. In addition to pulmonary complications, liver injury is not …

Anakinra authorized to treat severe coronavirus disease 2019; Sepsis breakthrough or time to reflect?

L Shapiro, S Scherger, C Franco-Paredes… - Frontiers in …, 2023 - frontiersin.org
Introduction The European Medicines Agency (EMA) and the United States Food and Drug
Administration (FDA) announced conditions for using recombinant human interleukin-1 …

Targeting autophagy regulation in NLRP3 inflammasome-mediated lung inflammation in COVID-19

YY Yong, L Zhang, YJ Hu, JM Wu, L Yan, YR Pan… - Clinical …, 2022 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) is an infectious disease caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Emerging evidence indicates that …

The role of platelets, neutrophils and endothelium in COVID-19 infection

E Falcinelli, E Petito, P Gresele - Expert Review of Hematology, 2022 - Taylor & Francis
Introduction COVID-19 is associated to an increased risk of thrombosis, as a result of a
complex process that involves the activation of vascular and circulating cells, the release of …

Advances in attractive therapeutic approach for macrophage activation syndrome in COVID-19

S Chen, C Zhang, D Chen, L Dong, T Chang… - Frontiers in …, 2023 - frontiersin.org
Nowadays, people have relaxed their vigilance against COVID-19 due to its declining
infection numbers and attenuated virulence. However, COVID-19 still needs to be concern …

[HTML][HTML] Regdanvimab improves disease mortality and morbidity in patients with COVID-19: A meta-analysis

M Yang, T Li, L Jiang, Y Wang, C Tran… - The Journal of …, 2022 - ncbi.nlm.nih.gov
We read with great interest that biologic medications might be a promising therapeutic
option in COVID-19. 1 Neutralizing monoclonal antibodies such as regdanvimab can reduce …

The safety of canakinumab in systemic juvenile idiopathic arthritis and autoinflammatory diseases in pediatric patients: a multicenter study

T Coşkuner, Ş Çağlayan, Ö Akgün… - Expert opinion on …, 2023 - Taylor & Francis
Objective To evaluate the safety of canakinumab using real-world data in patients with
systemic juvenile idiopathic arthritis (sJIA) and autoinflammatory diseases (AID). Research …

Comprehensive bioinformatics analysis and systems biology approaches to identify the interplay between COVID-19 and pericarditis

D Li, R Chen, C Huang, G Zhang, Z Li, X Xu… - Frontiers in …, 2024 - frontiersin.org
Background Increasing evidence indicating that coronavirus disease 2019 (COVID-19)
increased the incidence and related risks of pericarditis and whether COVID-19 vaccine is …