An important role of the immune system is in the surveillance for abnormal or transformed
cells, which is known as cancer immunosurveillance. Through this process, the first changes …

Breast cancer is the most common cancer in women worldwide and is a substantial public
health problem. Screening for breast cancer mainly relies on mammography, which leads to …

Tumor-infiltrating B cells (TIL-B) in breast cancer (BC) have previously been associated with
improved clinical outcomes; however, their roles in tumor immunity are not currently well …

Tumor-infiltrating B cells are an important component in the microenvironment but have
unclear anti-tumor effects. We enhanced our previous computational algorithm TRUST to …

Autoantibodies that recognize extracellular proteins (the exoproteome) exert potent
biological effects but are challenging to detect. Here, we developed rapid extracellular …

B cells and T cells are important components of the adaptive immune system and mediate
anticancer immunity. The T cell landscape in cancer is well characterized, but the …

Therapeutic antibodies targeting disease-associated antigens are key tools in the treatment
of cancer and autoimmunity. So far, therapeutic antibodies have targeted antigens that are …

Tumor immunotherapy is considered to be a novel and promising therapy for tumors and it
has recently become a hot research topic. The clinical success of tumor immunotherapy has …

Autoantibodies are well known as potentially highly harmful antibodies which attack the host
via binding to self-antigens, thus causing severe associated diseases and symptoms (eg …

Anti-cytokine autoantibodies and, in particular, anti-type I interferons are increasingly
described in association with immunodeficient, autoimmune, and immune-dysregulated …