Nuclear magnetic resonance (NMR) spectroscopy provides a unique toolbox of
experimental probes for studying dynamic processes on a wide range of timescales, ranging …

Overwhelming evidence now illustrates the defining role of atomic-scale protein flexibility in
biological events such as allostery, cell signaling, and enzyme catalysis. Over the years …

It is now common knowledge that enzymes are mobile entities relying on complex atomic-
scale dynamics and coordinated conformational events for proper ligand recognition and …

Pepsin-like aspartic proteases (PAPs) are a class of aspartic proteases which shares
tremendous structural similarity with human pepsin. One of the key structural features of …

Eukaryotic protein kinases (PKs) are a large family of proteins critical for cellular response to
external signals, acting as molecular switches. PKs propagate biochemical signals by …

Backbone chemical shift assignments for the Toho-1 β-lactamase (263 amino acids, 28.9
kDa) are reported based on triple resonance solution-state NMR experiments performed on …

Experimental methods are indispensable for the study of the function of biological
macromolecules, not just as static structures, but as dynamic systems that change …

Structural information of protein complexes is fundamental for the rational drug design and
improvement of vaccines and biosensors. Also, protein misassembly can have severe …

Glycocins are antimicrobial peptides with glycosylations, often an S-linked monosaccharide.
Their recent structure elucidation has brought forth questions about their mechanisms of …

Backbone assignments for the isolated α-subunit of Salmonella typhimurium tryptophan
synthase (TS) are reported based on triple resonance solution-state NMR experiments on a …