Iron overload causes iron deposition and accumulation in the liver, heart, skin, and other
tissues resulting in serious tissue damages. Significant blood clearance from iron and ferritin …

By performing regular blood transfusion and iron chelation therapy, most patients with beta
thalassemia major (BTM) now survive beyond the third decade of life. Liver disease is …

Background. The main causes of liver fibrosis in transfusion-dependent thalassemia major
are hepatitis C virus (HCV) infection and hepatic iron overload. The study aimed to assess …

Introduction: Thalassemia is hereditary anemia which requires lifelong transfusion as
treatment, and hepatitis viral infection is one of the risks of repeated transfusions. Hepatitis B …

Chronic hepatitis C (CHC) and iron overload are the main causes of liver disease in β-
thalassemia major (βTM). There is limited data regarding the course of CHC in this …

Background The course of hepatitis C infection (HCV) in patients with thalassemia has not
been adequately studied, and management has not been optimized. The current …

ABSTRACT Background: In Egypt, Thalassaemia is considered the most common
genetically determined haemolytic disease. Its high prevalence causes a significant burden …

Background Transfusion dependant patients are at a higher risk of acquiring bloodborne
infections even under conditions of safe transfusion. This study was designed to determine …

Objective: Detecting the current prevalence of hepatitis C virus (HCV) among Egyptian
multitransfused thalassemic patients and evaluating the risk of its transmission within their …

Background: Hepatitis is a serious blood born infection in patients with β-thalassemia major
(β-TM). There was no previous report on hepatitis prevalence in patients with β-TM in Zabol …