Long non-coding RNAs and rheumatoid arthritis: pathogenesis and clinical implications
Long non-coding RNAs (lncRNAs) are a class of noncoding RNAs with a length larger than
200 nucleotides that participate in various diseases and biological processes as they can …
200 nucleotides that participate in various diseases and biological processes as they can …
LncRNA expression profiles in systemic lupus erythematosus and rheumatoid arthritis: emerging biomarkers and therapeutic targets
H Wu, S Chen, A Li, K Shen, S Wang, S Wang… - Frontiers in …, 2021 - frontiersin.org
Systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA) are two common
multisystem autoimmune diseases that share, among others, many clinical manifestations …
multisystem autoimmune diseases that share, among others, many clinical manifestations …
Molecular mechanism of lncRNAs in pathogenesis and diagnosis of auto-immune diseases, with a special focus on lncRNA-based therapeutic approaches
Autoimmune diseases are a diverse set of conditions defined by organ damage due to
abnormal innate and acquired immune system responses. The pathophysiology of …
abnormal innate and acquired immune system responses. The pathophysiology of …
Dysregulation of lncRNAs in rheumatoid arthritis: biomarkers, pathogenesis and potential therapeutic targets
C Miao, L Bai, Y Yang, J Huang - Frontiers in pharmacology, 2021 - frontiersin.org
Rheumatoid arthritis (RA) is a chronic autoimmune disease of unknown etiology, mainly
manifested by persistent abnormal proliferation of fibroblast-like synoviocytes (FLSs) …
manifested by persistent abnormal proliferation of fibroblast-like synoviocytes (FLSs) …
[HTML][HTML] Non-coding RNAs in immunoregulation and autoimmunity: Technological advances and critical limitations
Immune cell function is critically dependent on precise control over transcriptional output
from the genome. In this respect, integration of environmental signals that regulate gene …
from the genome. In this respect, integration of environmental signals that regulate gene …
[HTML][HTML] Dysregulation of non-coding RNAs in rheumatoid arthritis
Rheumatoid arthritis (RA) is a chronic inflammatory disorder that is associated with both
genetic and environmental factors. Dysregulation of the immune response is the main …
genetic and environmental factors. Dysregulation of the immune response is the main …
[HTML][HTML] LncRNA PTGS2 regulates islet β-cell function through the miR-146a-5p/RBP4 axis and its diagnostic value in type 2 diabetes mellitus
Q Chen, Y He, X Wang, Y Zhu, Y Huang… - American Journal of …, 2021 - ncbi.nlm.nih.gov
Objective: To investigate the effect of long non-coding RNA (LncRNA) PTGS2 on islet β-cell
function via the miR-146a-5p/Retinol binding protein 4 (RBP4) axis and its diagnostic value …
function via the miR-146a-5p/Retinol binding protein 4 (RBP4) axis and its diagnostic value …
Silencing long non-coding RNA NEAT1 attenuates rheumatoid arthritis via the MAPK/ERK signalling pathway by downregulating microRNA-129 and microRNA-204
J Chen, X Luo, M Liu, L Peng, Z Zhao, C He, Y He - RNA biology, 2021 - Taylor & Francis
The participation of long noncoding RNAs (lncRNAs) and microRNAs (miRs) in the
progression of rheumatoid arthritis (RA) is a key area of investigation. The current study …
progression of rheumatoid arthritis (RA) is a key area of investigation. The current study …
[HTML][HTML] Non-coding natural antisense transcripts: Analysis and application
JC Krappinger, L Bonstingl, K Pansy, K Sallinger… - Journal of …, 2021 - Elsevier
Non-coding natural antisense transcripts (ncNATs) are regulatory RNA sequences that are
transcribed in the opposite direction to protein-coding or non-coding transcripts. These …
transcribed in the opposite direction to protein-coding or non-coding transcripts. These …
The potential role of serum expression profile of long non coding RNAs, Cox2 and HOTAIR as novel diagnostic biomarkers in systemic lupus erythematosus
Background The role of the long non-coding RNAs (lncRNAs) in the pathogenesis of
systemic lupus erythematosus (SLE) is mostly unknown, despite increasing evidence that …
systemic lupus erythematosus (SLE) is mostly unknown, despite increasing evidence that …