Synthetic 3D extracellular matrices (ECMs) find application in cell studies, regenerative
medicine, and drug discovery. While cells cultured in a monolayer may exhibit unnatural …

Cell culture in two dimensions has been routinely and diligently undertaken in thousands of
laboratories worldwide for the past four decades. However, the culture of cells in two …

In recent years neurodevelopmental problems in children have increased at a rate that
suggests lifestyle factors and chemical exposures as likely contributors. When …

Circulating tumor cells (CTCs) represent an interesting source of biomarkers for diagnosis,
prognosis, and the prediction of cancer recurrence, yet while they are extensively studied in …

In pancreatic ductal adenocarcinoma (PDAC), early onset of hypoxia triggers remodeling of
the extracellular matrix, epithelial-to-mesenchymal transition, increased cell survival, the …

Monitoring dynamic processes in complex cellular environments requires the integration of
uniformly distributed detectors within such three-dimensional (3D) networks, to an extent that …

Protein N-terminal methylation catalyzed by N-terminal methyltransferase 1 (NTMT1) is an
emerging methylation present in eukaryotes, playing important regulatory roles in various …

To obtain a multicellular MCF-7 spheroid model to mimic the three-dimensional (3D) of
tumors, the microwell liquid overlay (A) and hanging-drop/agar (B) methods were first …

Optical coherence microscopy (OCM) is a label-free, high-resolution, three-dimensional (3D)
imaging technique based on optical coherence tomography (OCT) and confocal microscopy …

As extracellular matrix (ECM) mimetic materials, hydrogels have been widely used for broad
biomedical applications. However, with so many physical or chemical cues in the matrix that …