Understanding viral and immune interplay during vertical transmission of HIV: implications for cure
O Amin, J Powers, KM Bricker, A Chahroudi - Frontiers in Immunology, 2021 - frontiersin.org
Despite the significant progress that has been made to eliminate vertical HIV infection, more
than 150,000 children were infected with HIV in 2019, emphasizing the continued need for …
than 150,000 children were infected with HIV in 2019, emphasizing the continued need for …
[PDF][PDF] Maternal Eosinophilic Responses in HIV-Positive Pregnant Women: Unraveling Immunological Dynamics for Improved Maternal-Fetal Health
Abstract Human Immunodeficiency Virus (HIV) infection during pregnancy introduces a
complex interplay between the maternal immune system and the imperative need for fetal …
complex interplay between the maternal immune system and the imperative need for fetal …
The impact of HIV and antiretroviral therapy on TB risk in children: a systematic review and meta-analysis
PJ Dodd, AJ Prendergast, C Beecroft, B Kampmann… - Thorax, 2017 - thorax.bmj.com
Background Children (< 15 years) are vulnerable to TB disease following infection, but no
systematic review or meta-analysis has quantified the effects of HIV-related …
systematic review or meta-analysis has quantified the effects of HIV-related …
Transfer of maternal immune cells by breastfeeding: maternal cytotoxic T lymphocytes present in breast milk localize in the Peyer's patches of the nursed infant
A Cabinian, D Sinsimer, M Tang, O Zumba, H Mehta… - PloS one, 2016 - journals.plos.org
Despite our knowledge of the protective role of antibodies passed to infants through breast
milk, our understanding of immunity transfer via maternal leukocytes is still limited. To …
milk, our understanding of immunity transfer via maternal leukocytes is still limited. To …
Passively acquired antibody-dependent cellular cytotoxicity (ADCC) activity in HIV-infected infants is associated with reduced mortality
In addition to direct effects on virus infectivity, antibodies mediate antibody-dependent
cellular cytotoxicity (ADCC), the killing of an antibody-coated virus-infected cell by cytotoxic …
cellular cytotoxicity (ADCC), the killing of an antibody-coated virus-infected cell by cytotoxic …
Maternal HIV infection influences the microbiome of HIV-uninfected infants
JM Bender, F Li, S Martelly, E Byrt, V Rouzier… - Science translational …, 2016 - science.org
More than 1 million HIV-exposed, uninfected infants are born annually to HIV-positive
mothers worldwide. This growing population of infants experiences twice the mortality of HIV …
mothers worldwide. This growing population of infants experiences twice the mortality of HIV …
Age at antiretroviral therapy initiation and cell-associated HIV-1 DNA levels in HIV-1-infected children
L Kuhn, M Paximadis, B Da Costa Dias, S Loubser… - PloS one, 2018 - journals.plos.org
Background The latent viral reservoir is the major obstacle to achieving HIV remission and
necessitates life-long antiretroviral therapy (ART) for HIV-infected individuals. Studies in …
necessitates life-long antiretroviral therapy (ART) for HIV-infected individuals. Studies in …
The importance of the microbiome in pediatrics and pediatric infectious diseases
T Gaufin, NH Tobin, GM Aldrovandi - Current opinion in pediatrics, 2018 - journals.lww.com
The importance of the microbiome in pediatrics and pediatric... : Current Opinion in Pediatrics
The importance of the microbiome in pediatrics and pediatric infectious diseases : Current …
The importance of the microbiome in pediatrics and pediatric infectious diseases : Current …
Prevention of the Vertical Transmission of HIV; A Recap of the Journey so Far
MC Cardenas, S Farnan, BL Hamel, MC Mejia Plazas… - Viruses, 2023 - mdpi.com
In 1989, one in four (25%) infants born to women living with HIV were infected; by the age of
2 years, there was 25% mortality among them due to HIV. These and other pieces of data …
2 years, there was 25% mortality among them due to HIV. These and other pieces of data …
Broadly neutralizing antibodies: What is needed to move from a rare event in HIV-1 infection to vaccine efficacy?
H Subbaraman, M Schanz, A Trkola - Retrovirology, 2018 - Springer
The elicitation of broadly neutralizing antibodies (bnAbs) is considered crucial for an
effective, preventive HIV-1 vaccine. Led by the discovery of a new generation of potent …
effective, preventive HIV-1 vaccine. Led by the discovery of a new generation of potent …