Methemoglobin (MHb) may arise from a variety of etiologies including genetic, dietary,
idiopathic, and toxicologic sources. Symptoms vary from mild headache to coma/death and …

Evidence-Based Case Review: Methemoglobinemia - PMC Back to Top Skip to main content
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Dapsone is useful in the treatment of a number of inflammatory conditions which are
characterized by neutrophil infiltration. It is the drug of choice for suppression of the …

The human cytochrome P450 enzyme system metabolises a wide array of xenobiotics to
pharmacologically inactive metabolites, and occasionally, to toxicologically active …

The objectives of this review are to describe the acquired and hereditary causes of
methemoglobinemia, to recommend the most sensitive diagnostic tests, and to enable …

Introduction: Pneumocystis pneumonia is a potentially life-threatening pulmonary infection
that occurs in immunocompromised individuals and HIV-infected patients with a low CD4 …

1. We have attempted to reduce dapsone‐dependent methaemoglobinaemia formation in
six dermatitis herpetiformis patients stabilised on dapsone by the co‐administration of …

Adverse drug reactions can be caused by the parent drug or a metabolite of that drug. The
metabolite may be stable or chemically reactive, the resultant toxicity being either a direct …

Methaemoglobin is a form of haemoglobin in which the ferrous (Fe 2+) ion contained in the
iron–porphyrin complex of haem is oxidised to its ferric (Fe 3+) state. Methaemoglobinaemia …

The differential incidence of adverse drug reactions (ADR) between trimethoprim-
sulfamethoxazole and dapsone might be explained, in part, by differences in the inherent …