Of all biologic matrices, decellularized extracellular matrix (dECM) has emerged as a
promising tool used either alone or when combined with other biologics in the fields of tissue …

Respiratory disease is the third leading cause of death in the industrialized world.
Consequently, the trachea, lungs, and cardiopulmonary vasculature have been the focus of …

Extracellular matrix (ECM) is a natural biomaterial scaffold that provides biochemical and
structural support to its surrounding cells, forming tissue and respective organs. These ECM …

Bioengineered lungs produced from patient-derived cells may one day provide an
alternative to donor lungs for transplantation therapy. Here we report the regeneration of …

With the advent of whole organ decellularization, extracellular matrix scaffolds suitable for
organ engineering were generated from numerous tissues, including the heart, lung, liver …

The extracellular matrix (ECM) of the lung plays several important roles in lung function, as it
offers a low resistant pathway that allows the exchange of gases, provides compressive …

The tissue turnover of unperturbed adult lung is remarkably slow. However, after injury or
insult, a specialised group of facultative lung progenitors become activated to replenish …

Effective clinical treatments for volumetric muscle loss resulting from traumatic injury or
resection of a large amount of muscle mass are not available to date. Tissue engineering …

End-stage renal disease (ESRD) is characterized by the progressive deterioration of renal
function that may compromise different tissues and organs. The major treatment indicated for …

Chronic respiratory diseases have collectively become a major public health concern and
have now taken form as one of the leading causes of mortality worldwide. Most chronic …