Effects of pesticide mixtures in human and animal models: An update of the recent literature

V Rizzati, O Briand, H Guillou… - Chemico-biological …, 2016 - Elsevier
This review aims to provide an update on our current knowledge of the various effects of
pesticide cocktails. We have collected data from studies conducted in mammalian models in …

Uncertainty surrounding the mechanism and safety of the post-harvest fungicide fludioxonil

TT Brandhorst, BS Klein - Food and Chemical Toxicology, 2019 - Elsevier
Fludioxonil is a phenylpyrrole pesticide that is applied to fruit and vegetable crops post-
harvest to minimize losses to mold, both during transport and at point of sale. Its …

Organophosphate pesticide chlorpyrifos impairs STAT1 signaling to induce dopaminergic neurotoxicity: Implications for mitochondria mediated oxidative stress …

N Singh, V Lawana, J Luo, P Phong, A Abdalla… - Neurobiology of …, 2018 - Elsevier
The organophosphate (OP) pesticide chlorpyrifos (CPF), used in agricultural settings,
induces developmental and neurological impairments. Recent studies using in vitro cell …

Toxic effects of fludioxonil on the growth, photosynthetic activity, oxidative stress, cell morphology, apoptosis, and metabolism of Chlorella vulgaris

X Liu, X Wang, F Zhang, X Yao, Z Qiao, J Deng… - Science of The Total …, 2022 - Elsevier
Fludioxonil is widely used in the control of crop diseases because of its broad spectrum and
high activity, but its presence is now common in waterways proximate to treated areas. This …

Microbial Antagonism Toward Botrytis Bunch Rot of Grapes in Multiple Field Tests Using One Bacillus ginsengihumi Strain and Formulated Biological Control …

C Calvo-Garrido, J Roudet, N Aveline… - Frontiers in plant …, 2019 - frontiersin.org
Botrytis bunch rot (BBR), caused by the necrotrophic fungus Botrytis cinerea, is a major
disease of wine and table grapes worldwide. Due to negative effects of pesticides on the …

Phenylpyrrole fungicides act on triosephosphate isomerase to induce methylglyoxal stress and alter hybrid histidine kinase activity

TT Brandhorst, IRL Kean, SM Lawry, DL Wiesner… - Scientific reports, 2019 - nature.com
Fludioxonil, a natural product of pyrrolnitrin, is a potent fungicide used on crops worldwide.
Drug action requires the presence of a group III hybrid histidine kinase (HHK) and the h igh …

The ascendance of microphysiological systems to solve the drug testing dilemma

EM Dehne, T Hasenberg, U Marx - Future science OA, 2017 - Taylor & Francis
The development of drugs is a process obstructed with manifold security and efficacy
concerns. Although animal models are still widely used to meet the diligence required, they …

The impact of pesticides on oxidative stress level in human organism and their activity as an endocrine disruptor

A Jabłońska-Trypuć, E Wołejko, U Wydro… - … Science and Health …, 2017 - Taylor & Francis
Pesticides cause serious environmental and health problems both to humans and animals.
The aim of this review is to discuss selected herbicides and fungicides regarding their mode …

Photodegradation of fludioxonil and other pyrroles: the importance of indirect photodegradation for understanding environmental fate and photoproduct formation

JN Apell, NC Pflug, K McNeill - Environmental science & …, 2019 - ACS Publications
Fludioxonil is a pyrrole-containing pesticide whose registration as a plant protection product
is currently under review in the United States and Europe. There are concerns over its …

Genotoxicity of mixtures of glyphosate and atrazine and their environmental transformation products before and after photoactivation

A Roustan, M Aye, M De Meo, C Di Giorgio - Chemosphere, 2014 - Elsevier
The photo-inducible cytogenetic toxicity of glyphosate, atrazine, aminomethyl phosphoric
acid (AMPA), desethyl-atrazine (DEA), and their various mixtures was assessed by the in …