[HTML][HTML] Connectome-based lesion-symptom mapping (CLSM): A novel approach to map neurological function

E Gleichgerrcht, J Fridriksson, C Rorden, L Bonilha - NeuroImage: Clinical, 2017 - Elsevier
Lesion-symptom mapping is a key tool in understanding the relationship between structure
and function in neuroscience as it can provide objective evidence about which regions are …

Anatomy of aphasia revisited

J Fridriksson, DB den Ouden, AE Hillis, G Hickok… - Brain, 2018 - academic.oup.com
In most cases, aphasia is caused by strokes involving the left hemisphere, with more
extensive damage typically being associated with more severe aphasia. The classical model …

Latent disconnectome prediction of long-term cognitive-behavioural symptoms in stroke

L Talozzi, SJ Forkel, V Pacella, V Nozais, E Allart… - Brain, 2023 - academic.oup.com
Stroke significantly impacts the quality of life. However, the long-term cognitive evolution in
stroke is poorly predictable at the individual level. There is an urgent need to better predict …

Contemporary approaches to the management of post-stroke apraxia of speech

A Basilakos - Seminars in speech and language, 2018 - thieme-connect.com
Apraxia of speech (AOS) is a motor speech disorder that disrupts the planning and
programming of speech motor movements. In the acute stage of stroke recovery, AOS …

Multivariate connectome-based symptom mapping in post-stroke patients: networks supporting language and speech

G Yourganov, J Fridriksson, C Rorden… - Journal of …, 2016 - Soc Neuroscience
Language processing relies on a widespread network of brain regions. Univariate post-
stroke lesion-behavior mapping is a particularly potent method to study brain–language …

Deep learning applied to whole‐brain connectome to determine seizure control after epilepsy surgery

E Gleichgerrcht, B Munsell, S Bhatia… - …, 2018 - Wiley Online Library
Objective We evaluated whether deep learning applied to whole‐brain presurgical structural
connectomes could be used to predict postoperative seizure outcome more accurately than …

Temporal lobe networks supporting the comprehension of spoken words

L Bonilha, AE Hillis, G Hickok, DB Den Ouden… - Brain, 2017 - academic.oup.com
Auditory word comprehension is a cognitive process that involves the transformation of
auditory signals into abstract concepts. Traditional lesion-based studies of stroke survivors …

Machine learning‐based multimodal prediction of language outcomes in chronic aphasia

S Kristinsson, W Zhang, C Rorden… - Human brain …, 2021 - Wiley Online Library
Recent studies have combined multiple neuroimaging modalities to gain further
understanding of the neurobiological substrates of aphasia. Following this line of work, the …

Regional white matter damage predicts speech fluency in chronic post-stroke aphasia

A Basilakos, PT Fillmore, C Rorden, D Guo… - Frontiers in human …, 2014 - frontiersin.org
Recently, two different white matter regions that support speech fluency have been
identified: the aslant tract and the anterior segment of the arcuate fasciculus (ASAF). The …

Success of anomia treatment in aphasia is associated with preserved architecture of global and left temporal lobe structural networks

L Bonilha, E Gleichgerrcht, T Nesland… - … and neural repair, 2016 - journals.sagepub.com
Background and Objective. Targeted speech therapy can lead to substantial naming
improvement in some subjects with anomia following dominant-hemisphere stroke. We …