Here, we addressed the pharmacology and toxicology of synthetic organoselenium
compounds and some naturally occurring organoselenium amino acids. The use of …

The emergence of new fungal pathogens makes the development of new antifungal drugs a
medical imperative that in recent years motivates the talents of numerous investigators …

Background Ebselen, an organoselenium compound and a clinically safe molecule has
been reported to possess potent antifungal activity, but its antifungal mechanism of action …

Control of fungal pathogens is increasingly problematic due to the limited number of
effective drugs available for antifungal therapy. Conventional antifungal drugs could also …

The extensive use of fluconazole (FLC) and other azole drugs has caused the emergence
and rise of azole-resistant fungi. The fungistatic nature of FLC in combination with toxicity …

As microbial resistance to drugs continues to rise at an alarming rate, finding new ways to
combat pathogens is an issue of utmost importance. Development of novel and specific …

Ebselen is a synthetic organoselenium radical scavenger compound that possesses
glutathione peroxidase-like activity and its own unique bioactivity by reacting with thiols …

Background: Sulfur-containing compounds represent an important class of chemical
compounds due to their wide range of biological and pharmaceutical properties. Moreover …

The literature on cyclic sulfinamides (put simply, sultims) published from 1989 to 2022 has
been summarized and reviewed. The information is divided into two sections: the analysis of …

Fungal infections are one of the most prevalent diseases in the world and there is a lack of
new antifungal drug development for these diseases. We conducted a systematic review of …