[HTML][HTML] Pulmonary delivery of siRNA against acute lung injury/acute respiratory distress syndrome

M Zoulikha, Q Xiao, GF Boafo, MA Sallam… - … Pharmaceutica Sinica B, 2022 - Elsevier
The use of small interfering RNAs (siRNAs) has been under investigation for the treatment of
several unmet medical needs, including acute lung injury/acute respiratory distress …

Approved nanomedicine against diseases

Y Jia, Y Jiang, Y He, W Zhang, J Zou, KT Magar… - Pharmaceutics, 2023 - mdpi.com
Nanomedicine is a branch of medicine using nanotechnology to prevent and treat diseases.
Nanotechnology represents one of the most effective approaches in elevating a drug's …

Responsive hydrogels based on triggered click reactions for liver cancer

JQ Zhu, H Wu, ZL Li, XF Xu, H Xing… - Advanced …, 2022 - Wiley Online Library
Globally, liver cancer, which is one of the major cancers worldwide, has attracted the
growing attention of technological researchers for its high mortality and limited treatment …

Nanosuspensions in ophthalmology: Overcoming challenges and enhancing drug delivery for eye diseases

S Fathi-Karkan, NA Ramsheh, H Arkaban… - International Journal of …, 2024 - Elsevier
This review article provides a comprehensive overview of the advancements in using
nanosuspensions for controlled drug delivery in ophthalmology. It highlights the significance …

[HTML][HTML] Lipid carriers for mRNA delivery

W Zhang, Y Jiang, Y He, H Boucetta, J Wu… - … Pharmaceutica Sinica B, 2023 - Elsevier
Messenger RNA (mRNA) is the template for protein biosynthesis and is emerging as an
essential active molecule to combat various diseases, including viral infection and cancer …

Confronting antifungal resistance, tolerance, and persistence: advances in drug target discovery and delivery systems

L Chen, L Zhang, Y Xie, Y Wang, X Tian, W Fang… - Advanced Drug Delivery …, 2023 - Elsevier
Human pathogenic fungi pose a serious threat to human health and safety. Unfortunately,
the limited number of antifungal options is exacerbated by the continuous emergence of …

Paving the way for affordable and equitable liposomal amphotericin B access worldwide

JSF Lee, RM Cohen, RA Khan, J Burry… - The Lancet Global …, 2024 - thelancet.com
Amphotericin B has long been crucial for treating many serious infectious diseases, such as
invasive fungal infections and visceral leishmaniasis, particularly for patients who are …

New antifungal strategies: drug combination and co-delivery

P Zhu, Y Li, T Guo, S Liu, RJ Tancer, C Hu… - Advanced Drug Delivery …, 2023 - Elsevier
The growing occurrence of invasive fungal infections and the mounting rates of drug
resistance constitute a significant menace to human health. Antifungal drug combinations …

Gout therapeutics and drug delivery

X Peng, X Li, B Xie, Y Lai, A Sosnik, H Boucetta… - Journal of Controlled …, 2023 - Elsevier
Gout is a common inflammatory arthritis caused by persistently elevated uric acid levels.
With the improvement of people's living standards, the consumption of processed food and …

Antifungal therapy: Novel drug delivery strategies driven by new targets

S Wu, R Song, T Liu, C Li - Advanced Drug Delivery Reviews, 2023 - Elsevier
In patients with compromised immunity, invasive fungal infections represent a significant
cause of mortality. Given the limited availability and drawbacks of existing first-line antifungal …