Many processes in the human body—including brain function—are regulated over the 24-
hour cycle, and there are strong associations between disrupted circadian rhythms (for …

Epidemiological studies provided the first evidence suggesting a connection between the
circadian clock and human health. Mutant mice convincingly demonstrate the principle that …

BACKGROUND. The circadian clock is a fundamental and pervasive biological program that
coordinates 24-hour rhythms in physiology, metabolism, and behavior, and it is essential to …

The molecular circadian clock and symbiotic host-microbe relationships both evolved as
mechanisms that enhance metabolic responses to environmental challenges. The gut …

A variety of organisms including mammals have evolved a 24h, self-sustained timekeeping
machinery known as the circadian clock (biological clock), which enables to anticipate …

The objective of chronotherapy is to optimize medical treatments taking into account the
body's circadian rhythms. Chronotherapy is referred to and practiced in two different …

The skin is the largest human organ with a circadian clock that regulates its function.
Although circadian rhythms in specific functions are known, rhythms in the proximal clock …

The unprecedented restrictions imposed due to the COVID-19 pandemic altered our daily
habits and severely affected our well-being and physiology. The effect of these changes is …

Working remotely from home during the COVID-19 pandemic has resulted in significant
shifts and disruptions in the personal and work lives of millions of information workers and …

Alzheimer's disease (AD) is the most common form of dementia and affects over 45 million
people worldwide. Both type-2-diabetes (T2D), a metabolic condition associated with aging …