[HTML][HTML] Beyond HIV infection: neglected and varied impacts of CCR5 and CCR5Δ32 on viral diseases
The interactions between chemokine receptors and their ligands may affect susceptibility to
infectious diseases as well as their clinical manifestations. These interactions mediate both …
infectious diseases as well as their clinical manifestations. These interactions mediate both …
Is the CCR5 Δ 32 mutation associated with immune system-related diseases?
K Ghorban, M Dadmanesh, G Hassanshahi, M Momeni… - Inflammation, 2013 - Springer
Hypersensitivity and autoimmunity are the main features of immune system-related diseases
such as type 2 diabetes (T2D), multiple sclerosis (MS), and asthma. It has been established …
such as type 2 diabetes (T2D), multiple sclerosis (MS), and asthma. It has been established …
The expression of miR‐125b‐5p is increased in the serum of patients with chronic hepatitis B infection and inhibits the detection of hepatitis B virus surface antigen
M Ninomiya, Y Kondo, O Kimura… - Journal of viral …, 2016 - Wiley Online Library
Micro RNA s were first discovered as small endogenous RNA molecules and some viruses
have been reported to interact with host mi RNA s. By investigating mi RNA expression in …
have been reported to interact with host mi RNA s. By investigating mi RNA expression in …
CCR5 plays important roles in hepatitis B infection
In humans, hepatitis B virus (HBV) is the most prevalent and the main infectious agent that
leads to liver disease. Previous investigations identified that long-term HBV-infected patients …
leads to liver disease. Previous investigations identified that long-term HBV-infected patients …
SATB1 prevents immune cell infiltration by regulating chromatin organization and gene expression of a chemokine gene cluster in T cells
B Wang, Q Bian - Communications Biology, 2024 - nature.com
SATB1, a key regulator of T cell development, governs lineage-specific transcriptional
programs upon T cell activation. The absence of SATB1 has been linked to the initiation and …
programs upon T cell activation. The absence of SATB1 has been linked to the initiation and …
NK cells in hepatitis B virus infection: a potent target for immunotherapy
Z Shabani, M Bagheri, M Zare-Bidaki… - Archives of …, 2014 - Springer
Viruses, including hepatitis B virus (HBV), are the most prevalent and infectious agents that
lead to liver disease in humans. Hepatocellular carcinoma (HCC) and cirrhosis of the liver …
lead to liver disease in humans. Hepatocellular carcinoma (HCC) and cirrhosis of the liver …
Metabolomics as an Approach to Characterise the Contrasting Roles of CCR5 in the Presence and Absence of Disease
A Rautenbach, AA Williams - International journal of molecular sciences, 2020 - mdpi.com
Chemokine receptors such as CC chemokine receptor 5 (CCR5) are activated through
interaction with their ligands and are well known for their role in chemotaxis and signal …
interaction with their ligands and are well known for their role in chemotaxis and signal …
CCR5-Δ32 gene polymorphism is associated with retinopathy in patients with type 1 diabetes
B Słomiński, U Ławrynowicz, J Myśliwska… - Molecular and cellular …, 2017 - Elsevier
Aim The aim of the study was to assess the relationship between the CCR5-Δ32
polymorphism and the risk of diabetic retinopathy (DR) in patients with DM1. Methods We …
polymorphism and the risk of diabetic retinopathy (DR) in patients with DM1. Methods We …
CCR2 and CCR5 genes polymorphisms in women with cervical lesions from Pernambuco, Northeast Region of Brazil: a case-control study
EUD Santos, GDC Lima, ML Oliveira… - Memórias do Instituto …, 2016 - SciELO Brasil
Polymorphisms in chemokine receptors play an important role in the progression of cervical
intraepithelial neoplasia (CIN) to cervical cancer (CC). Our study examined the association …
intraepithelial neoplasia (CIN) to cervical cancer (CC). Our study examined the association …
Decreased expressions of STING but not IRF3 molecules in chronic HBV infected patients
M Karimi-Googheri, H Daneshvar… - Archives of Iranian …, 2015 - journalaim.com
CONTEXT: The stimulator of interferon genes (STING) induces the activation of interferon
regulatory factor 3 (IRF3) in response to intracellular viral double-stranded (ds) DNA. The …
regulatory factor 3 (IRF3) in response to intracellular viral double-stranded (ds) DNA. The …