Ten years of the horse reference genome: insights into equine biology, domestication and population dynamics in the post‐genome era

T Raudsepp, CJ Finno, RR Bellone… - Animal …, 2019 - Wiley Online Library
The horse reference genome from the Thoroughbred mare Twilight has been available for a
decade and, together with advances in genomics technologies, has led to unparalleled …

A high resolution atlas of gene expression in the domestic sheep (Ovis aries)

EL Clark, SJ Bush, MEB McCulloch, IL Farquhar… - PLoS …, 2017 - journals.plos.org
Sheep are a key source of meat, milk and fibre for the global livestock sector, and an
important biomedical model. Global analysis of gene expression across multiple tissues has …

Functional annotation of the animal genomes: an integrated annotation resource for the horse

S Peng, AR Dahlgren, CG Donnelly, EN Hales… - PLoS …, 2023 - journals.plos.org
The genomic sequence of the horse has been available since 2009, providing critical
resources for discovering important genomic variants regarding both animal health and …

Re-assembly, quality evaluation, and annotation of 678 microbial eukaryotic reference transcriptomes

LK Johnson, H Alexander, CT Brown - Gigascience, 2019 - academic.oup.com
Background De novo transcriptome assemblies are required prior to analyzing RNA
sequencing data from a species without an existing reference genome or transcriptome …

A missense mutation in MYH1 is associated with susceptibility to immune-mediated myositis in Quarter Horses

CJ Finno, G Gianino, S Perumbakkam, ZJ Williams… - Skeletal muscle, 2018 - Springer
Background The cause of immune-mediated myositis (IMM), characterized by recurrent,
rapid-onset muscle atrophy in Quarter Horses (QH), is unknown. The histopathologic …

“Adopt-a-tissue” initiative advances efforts to identify tissue-specific histone marks in the mare

NB Kingsley, NA Hamilton, G Lindgren… - Frontiers in …, 2021 - frontiersin.org
Methods All ChIP-Seq assays were performed by Diagenode ChIP-Seq Profiling Service
(Diagenode, Cat# G02010000, Liège, Belgium). Summarized experimental procedures are …

Identification of long non-coding RNA in the horse transcriptome

EY Scott, T Mansour, RR Bellone, CT Brown… - BMC genomics, 2017 - Springer
Background Efforts to resolve the transcribed sequences in the equine genome have
focused on protein-coding RNA. The transcription of the intergenic regions, although …

New insights in equine steroidogenesis: an in-depth look at steroid signaling in the placenta

SC Loux, AJ Conley, KE Scoggin, HES Ali… - …, 2020 - rep.bioscientifica.com
Steroid production varies widely among species, with these differences becoming more
pronounced during pregnancy. As a result, each species has its own distinct pattern of …

Adding exogenous biglycan or decorin improves tendon formation for equine peritenon and tendon proper cells in vitro

MY Pechanec, TN Boyd, K Baar… - BMC musculoskeletal …, 2020 - Springer
Background Tendon injuries amount to one of the leading causes of career-ending injuries
in horses due to the inability for tendon to completely repair and the high reinjury potential …

Next-generation sequencing in equine genomics

JL Petersen, SJ Coleman - Veterinary Clinics: Equine …, 2020 - vetequine.theclinics.com
The sequencing and assembly of a reference genome for the horse has been revolutionary
for investigation of horse health and performance. Since its publication, 1 the reference …