Forced degradation and impurity profiling: recent trends in analytical perspectives

D Jain, PK Basniwal - Journal of pharmaceutical and biomedical analysis, 2013 - Elsevier
This review describes an epigrammatic impression of the recent trends in analytical
perspectives of degradation and impurities profiling of pharmaceuticals including active …

[HTML][HTML] Impurity profiling of drugs towards safety and efficacy: theory and practice

KR Dhangar, RB Jagtap, SJ Surana… - Journal of the Chilean …, 2017 - SciELO Chile
Last decade has witnessed enormous changes in the studies of impurity profiling of drugs
which can be reflected from pharmacopoeia and regulatory guidelines. The present review …

Determination of polycyclic aromatic hydrocarbons and their nitrated and oxygenated derivatives in coffee brews using an efficient cold fiber-solid phase …

RR Dos Santos, LDV Leal… - … of Chromatography A, 2019 - Elsevier
Polycyclic aromatic hydrocarbons (PAHs) are food contaminants; besides, their oxygenated
(oxy-PAHs) and nitrated (nitro-PAHs) derivatives have also been detected in some foods …

Optimization of the amount of ZnO, CuO, and Ag nanoparticles on antibacterial properties of low-density polyethylene (LDPE) films using the response surface method

S Dehghani, SH Peighambardoust… - Food Analytical …, 2021 - Springer
Application of metallic nanoparticles (NPs) including silver (Ag), copper oxide (CuO), and
zinc oxide (ZnO) has been individually investigated in a polyethylene matrix. Since the …

Desirability-based optimization and its sensitivity analysis for the perindopril and its impurities analysis in a microemulsion LC system

A Malenović, Y Dotsikas, M Mašković… - Microchemical …, 2011 - Elsevier
In the current paper the application of multiobjective optimization (MOOP) technique, via
Derringer's desirability function, to a microemulsion liquid chromatographic (MELC) method …

Stepwise optimization approach for improving LC‐MS/MS analysis of zwitterionic antiepileptic drugs with implementation of experimental design

N Kostić, Y Dotsikas, A Malenović… - Journal of Mass …, 2013 - Wiley Online Library
In this article, a step‐by‐step optimization procedure for improving analyte response with
implementation of experimental design is described. Zwitterionic antiepileptics, namely …

D-optimal design for electrochemical simultaneous determination of bentazon and fenamiphos in natural waters

L Codognoto, TS Lima, FR Simões… - International Journal …, 2023 - Taylor & Francis
In this study, we proposed a new electroanalytical methodology using a boron-doped
diamond electrode (BDD), associated with factorial design for simultaneous and selective …

Jointly handling potency and toxicity of antimicrobial peptidomimetics by simple rules from desirability theory and chemoinformatics

M Cruz-Monteagudo, F Borges… - Journal of chemical …, 2011 - ACS Publications
Today, emerging and increasing resistance to antibiotics has become a threat to public
health worldwide. Antimicrobial peptides have unique action mechanisms making them an …

Optimization of artificial neural networks for modeling of atorvastatin and its impurities retention in micellar liquid chromatography

A Malenović, B Jančić-Stojanović, N Kostić, D Ivanović… - Chromatographia, 2011 - Springer
Abstract Artificial Neural Networks (ANNs) present a powerful tool for the modeling of
chromatographic retention. In this paper, the main objective was to use ANNs as a tool in …

A green liquid chromatographic method using ethanol in mobile phase for the determination of nimesulide and naproxen in gel formulations

S Yıldırım - Turkish Journal of Analytical Chemistry, 2023 - dergipark.org.tr
Dеtеrmination of nonsteroidal anti-inflammatory drugs (NSAIDs) in pharmacеutical
formulations hеlps to еnsurе that thеy arе manufacturеd to thе corrеct spеcifications …