Role of oxidative stress in pathophysiology of nonalcoholic fatty liver disease

M Masarone, V Rosato, M Dallio… - Oxidative medicine …, 2018 - Wiley Online Library
Liver steatosis without alcohol consumption, namely, nonalcoholic fatty liver disease
(NAFLD), is a common hepatic condition that encompasses a wide spectrum of …

Genetics and epigenetics of NAFLD and NASH: Clinical impact

M Eslam, L Valenti, S Romeo - Journal of hepatology, 2018 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is now recognised as the most common liver
disease worldwide. It encompasses a broad spectrum of conditions, from simple steatosis …

Oxidative stress as a critical factor in nonalcoholic fatty liver disease pathogenesis

S Spahis, E Delvin, JM Borys, E Levy - Antioxidants & redox …, 2017 - liebertpub.com
Significance: Nonalcoholic fatty liver disease (NAFLD), characterized by liver triacylglycerol
build-up, has been growing in the global world in concert with the raised prevalence of …

Oxidative stress in NAFLD: role of nutrients and food contaminants

C Rives, A Fougerat, S Ellero-Simatos, N Loiseau… - Biomolecules, 2020 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is often the hepatic expression of metabolic
syndrome and its comorbidities that comprise, among others, obesity and insulin-resistance …

Dehydroabietic acid improves nonalcoholic fatty liver disease through activating the Keap1/Nrf2-ARE signaling pathway to reduce ferroptosis

G Gao, Z Xie, E Li, Y Yuan, Y Fu, P Wang… - Journal of natural …, 2021 - Springer
The accumulation of iron-dependent lipid peroxides is one of the important causes of
NAFLD. The purpose of this study is to explore the effect of dehydroabietic acid (DA) on …

Ceruloplasmin gene variants are associated with hyperferritinemia and increased liver iron in patients with NAFLD

E Corradini, E Buzzetti, P Dongiovanni, S Scarlini… - Journal of …, 2021 - Elsevier
Background & Aims Non-alcoholic fatty liver disease (NAFLD) is a multifactorial disorder
resulting from genetic and environmental factors. Hyperferritinemia has been associated …

Genetic factors in the pathogenesis of nonalcoholic fatty liver and steatohepatitis

P Dongiovanni, S Romeo… - BioMed research …, 2015 - Wiley Online Library
Liver fat accumulation generally related to systemic insulin resistance characterizes
nonalcoholic fatty liver disease (NAFLD), which in the presence of nonalcoholic …

[HTML][HTML] Iron and non-alcoholic fatty liver disease

LJ Britton, VN Subramaniam… - World journal of …, 2016 - ncbi.nlm.nih.gov
The mechanisms that promote liver injury in non-alcoholic fatty liver disease (NAFLD) are
yet to be thoroughly elucidated. As such, effective treatment strategies are lacking and novel …

Genetics of nonalcoholic fatty liver disease

P Dongiovanni, L Valenti - Metabolism, 2016 - Elsevier
Epidemiological, familial, and twin studies indicate that non-alcoholic fatty liver disease, now
the leading cause of liver damage in developed countries, has a strong heritability. The …

[HTML][HTML] Dysregulation of iron and copper homeostasis in nonalcoholic fatty liver

E Aigner, G Weiss, C Datz - World journal of hepatology, 2015 - ncbi.nlm.nih.gov
Elevated iron stores as indicated by hyperferritinemia with normal or mildly elevated
transferrin saturation and mostly mild hepatic iron deposition are a characteristic finding in …