Circadian Regulation of Apolipoproteins in the Brain: Implications in Lipid Metabolism and Disease

CH Lee, CE Murrell, A Chu, X Pan - International Journal of Molecular …, 2023 - mdpi.com
The circadian rhythm is a 24 h internal clock within the body that regulates various factors,
including sleep, body temperature, and hormone secretion. Circadian rhythm disruption is …

Serum levels of α-Klotho are correlated with cerebrospinal fluid levels and predict measures of cognitive function

P Kundu, B Zimmerman, JF Quinn… - Journal of …, 2022 - content.iospress.com
Background: α-klotho might play a role in neurodegenerative diseases. Objective: To
determine levels of α-klotho and apoE in serum and cerebrospinal fluid (CSF) samples and …

Ionising radiation exposure-induced regulation of selected biomarkers and their impact in cancer and treatment

Y Mzizi, S Mbambara, B Moetlhoa… - Frontiers in Nuclear …, 2024 - frontiersin.org
Ionising radiation (IR) is a form of energy that travels as electromagnetic waves or particles.
While it is vital in medical and occupational health settings, IR can also damage DNA …

Do APOE4, malnutrition, and long COVID-19 compound the risk factors for stroke in adverse environments?

AV Buzaglo, CMAG Vieira, GCV Ciurleo… - Frontiers in …, 2024 - frontiersin.org
expressed in glial cells and is recognized to bind to brain amyloid plaques and is a culprit of
unbalanced neuroinflammatory responses in Alzheimer's disease (AD) patients and …

Serum soluble alpha-klotho klotho and cognitive functioning in older adults aged 60 and 79: an analysis of cross-sectional data of the National Health and Nutrition …

S Ge, F Dong, C Tian, CH Yang, M Liu, J Wei - BMC geriatrics, 2024 - Springer
Objectives Klotho, consisting of membrane klotho and soluble alpha-klotho, is found to be
associated with better cognitive outcomes in small samples of the aged population. We …