Biocatalysis has become an important tool in chemical synthesis, allowing access to
complex molecules with high levels of activity and selectivity and with low environmental …

Synthetic biology is touted as the next industrial revolution as it promises access to greener
biocatalytic syntheses to replace many industrial organic chemistries. Here, it is shown to …

Cytochrome P450 BM3 monooxygenase is the topic of extensive research as many
researchers have evolved this enzyme to generate a variety of products. However, the …

Retrosynthesis aims to efficiently plan the synthesis of desirable chemicals by strategically
breaking down molecules into readily available building block compounds. Having a long …

Recent advances in bioeconomy allow a holistic view of existing and new process chains
and enable novel production routines continuously advanced by academia and industry. All …

A revolution in the field of biocatalysis has enabled scalable access to compounds of high
societal values using enzymes. The construction of biocatalytic routes relies on the reservoir …

Enzyme research is important for the development of various scientific fields such as
medicine and biotechnology. Enzyme databases facilitate this research by providing a wide …

Organic synthesis often requires multiple steps where a functional group (FG) is concealed
from reaction by a protecting group (PG). Common PGs include N-carbobenzyloxy (Cbz or …

The chemical industry can now seize the opportunity to improve the sustainability of its
processes by replacing fossil carbon sources with renewable alternatives such as CO2 …

The synthesis of nitriles is of utmost importance for preparative organic chemistry. The
classical routes are often associated with disadvantages such as toxicity of the reagents and …