[HTML][HTML] Medicinally Privileged Natural Chalcones: Abundance, Mechanisms of Action, and Clinical Trials

SM Villa, J Heckman, D Bandyopadhyay - International Journal of …, 2024 - mdpi.com
Chalcones have been utilized for centuries as foods and medicines across various cultures
and traditions worldwide. This paper concisely overviews their biosynthesis as specialized …

[HTML][HTML] A Review of Experimental Studies on Natural Chalcone-Based Therapeutic Targeting of Genes and Signaling Pathways in Type 2 Diabetes Complications

NA Alsharairi - Genes, 2024 - ncbi.nlm.nih.gov
Diabetes mellitus type 2 (T2DM) is a common chronic condition that presents as unsettled
hyperglycemia (HG) and results from insulin resistance (IR) and β-cell dysfunction. T2DM is …

The Chemopreventive Impact of Diet-Derived Phytochemicals on the Adipose Tissue and Breast Tumor Microenvironment Secretome

N Akla, C Veilleux, B Annabi - Nutrition and Cancer, 2024 - Taylor & Francis
Cancer cells-derived extracellular vesicles can trigger the transformation of adipose-derived
mesenchymal stem cells (ADMSC) into a pro-inflammatory, cancer-associated adipocyte …

The Synthesis of 2′-Hydroxychalcones under Ball Mill Conditions and Their Biological Activities

I Abid, W Moslah, S Cojean, N Imbert, PM Loiseau… - Molecules, 2024 - mdpi.com
Chalcones are polyphenols that belong to the flavonoids family, known for their broad
pharmacological properties. They have thus attracted the attention of chemists for their …

The Role of Licorice Chalcones as Molecular Genes and Signaling Pathways Modulator—A Review of Experimental Implications for Nicotine-Induced Non-Small Cell …

NA Alsharairi - Current Issues in Molecular Biology, 2024 - mdpi.com
Lung cancer (LC) represents the leading cause of global cancer deaths, with cigarette
smoking being considered a major risk factor. Nicotine is a major hazardous compound in …

Ameliorative Effects of Oleoyl Chalcones on Liver and Cardiac Tissues Oxidative Damage and Hypertrophy Induced by High Fat Diet in Rats

MRE Aly, AAMA Khathamy, HH Saad, FA Fared… - The First International …, 2023 - Springer
Abstract High-fat diet (HFD)-induced obesity could lead to cardiac dysfunction, NASH, and
liver fibrosis. Oleoyl chalcones is a common nontoxic polyphenol having a broad range of …