Proliferation increasing genetic engineering in human corneal endothelial cells: a literature review

W Arras, H Vercammen, S Ní Dhubhghaill… - Frontiers in …, 2021 - frontiersin.org
The corneal endothelium is the inner layer of the cornea. Despite comprising only a
monolayer of cells, dysfunction of this layer renders millions of people visually impaired …

Molecular dissection on inhibition of Ras-induced cellular senescence by small t antigen of SV40

D Shang, T Zhou, X Zhuang, Y Wu, H Liu… - Cellular and Molecular Life …, 2022 - Springer
Abstract Simian virus 40 (SV40) is a potentially oncogenic virus of monkey origin.
Transmission, prevalence, and pathogenicity rates of SV40 are unclear, but infection can …

Phosphorylation of PBX2, a novel downstream target of mTORC1, is determined by GSK3 and PP1

R Wada, S Fujinuma, H Nakatsumi… - The Journal of …, 2023 - academic.oup.com
Mechanistic target of rapamycin complex 1 (mTORC1) is a serine–threonine kinase that is
activated by extracellular signals, such as nutrients and growth factors. It plays a key role in …

[PDF][PDF] 小鼠角膜上皮细胞永生化细胞系的建立及表型鉴定

白莹, 王一卉, 葛欢欢, 卞雯晗, 陈鹏 - 精准医学杂志, 2024 - jpmed.qdu.edu.cn
目的探讨小鼠角膜上皮细胞永生化细胞系的建立方法, 并鉴定其表型的稳定性.
方法提取小鼠角膜上皮原代细胞, 以猴空泡病毒40 大T 抗原(SV40-LT) 慢病毒感染小鼠角膜上皮 …

Label-free fluorescent determination of simian virus 40 using triplex DNA and G-quadruplex/N-methyl mesoporphyrin IX

M Wang, L Zhao, Y Wen, Y Wu, Y Li - Analytical Letters, 2021 - Taylor & Francis
Abstract Simian virus 40 (SV40) causes multiple diseases due to its low immunogenicity and
strong infectivity. Here, the development of a label-free fluorescent sensor designed to …

[PDF][PDF] Phosphorylation of PBX2, a novel downstream target of mTORC1, is determined by GSK3 and PP1

和田玲緒名 - 2023 - catalog.lib.kyushu-u.ac.jp
Abbreviations: DAPI, 4', 6-diamidino-2-phenylindole; DMSO, dimethyl sulfoxide; 22 ERK,
extracellular signal–regulated kinase; FOXK1, forkhead box K1; GSK3, glycogen 23 …

SAMHD1 promotes oncogene-induced replication stress

SM Zhang, JM Calderón-Montaño, SG Rudd - bioRxiv, 2020 - biorxiv.org
Oncogenes induce DNA replication stress in cancer cells. Although this was established
more than a decade ago, we are still unravelling the molecular underpinnings of this …