The phospholipase A2 (PLA2) and l-amino acid oxidase (LAAO) are two major enzymes
found in the venoms from most snake species. These enzymes have been structurally and …

For more than half a century, cytotoxic agents have been investigated as a possible
treatment for cancer. Research on animal venoms has revealed their high toxicity on tissues …

Muscle necrosis is a potential clinical complication of snakebite envenomings, which in
severe cases can lead to functional or physical sequelae such as disability or amputation …

Many active secretions produced by animals have been employed in the development of
new drugs to treat diseases such as hypertension and cancer. Snake venom toxins …

Snake venom contains a cocktail of compounds dominated by proteins and peptides, which
make up the toxin. The toxin components of snake venom attack several targets in the …

Snake venoms are natural sources of biologically active molecules that are able to act
selectively and specifically on different cellular targets, modulating physiological functions …

Myotoxin-II, a phospholipase A 2 (PLA 2)-like protein found in Bothrops asper venom,
causes rapid necrosis of muscle fibers in spite of lacking enzymatic activity. This toxic action …

Background: Snake venom phospholipases A2 (PLA2s) have been reported to induce
myotoxic, neurotoxic, hemolytic, edematogenic, cytotoxic and proinflammatory effects. This …

The emergence of antibiotic resistance drives an essential race against time to reveal new
molecular structures capable of addressing this alarming global health problem. Snake …

Abstract Background Phospholipases A 2 (PLA 2 s) are abundant components of snake
venoms that have been extensively studied due to their pharmacological and …