Ferroptosis as a mechanism of non-ferrous metal toxicity

M Aschner, AV Skalny, AC Martins, AI Sinitskii… - Archives of …, 2022 - Springer
Ferroptosis is a recently discovered form of regulated cell death, implicated in multiple
pathologies. Given that the toxicity elicited by some metals is linked to alterations in iron …

Low-dose chronic lead exposure increases systolic arterial pressure and vascular reactivity of rat aortas

EA Silveira, FDM Siman, T de Oliveira Faria… - Free Radical Biology …, 2014 - Elsevier
Chronic lead exposure induces hypertension affecting endothelial function. We investigated
whether low-concentration lead exposure alters blood pressure and vascular reactivity …

Antioxidant and Nephroprotective Effects of Okra Pods Extract (Abelmoschus esculentus L.) against Lead Acetate‐Induced Toxicity in Mice

SPA Wahyuningsih, NII Savira, DW Anggraini… - …, 2020 - Wiley Online Library
In this study, we determine the curative effects of okra pods (Abelmoschus esculentus L.)
extract against lead acetate toxicity in mice kidney. n‐Hexane, ethyl acetate, and methanol …

Association between blood lead and blood pressure: a population-based study in Brazilian adults

ACB Almeida Lopes, EK Silbergeld, A Navas-Acien… - Environmental …, 2017 - Springer
Background Environmental lead exposure among adults may increase blood pressure and
elevate the risk of hypertension. The availability of data on blood lead levels (BLL) in adult …

Low level and sub-chronic exposure to methylmercury induces hypertension in rats: nitric oxide depletion and oxidative damage as possible mechanisms

D Grotto, MM de Castro, GRM Barcelos, SC Garcia… - Archives of …, 2009 - Springer
Increased risk of hypertension after methylmercury (MeHg) exposure has been suggested.
However, the underlying mechanisms are not well explored. In this paper, we have analyzed …

Elevated blood lead levels in a riverside population in the Brazilian Amazon

F Barbosa Jr, M Fillion, M Lemire, CJS Passos… - Environmental …, 2009 - Elsevier
Lead (Pb) is recognized as one of the most toxic metals. Sources of Pb exposure have been
widely documented in North America, and the removal of Pb additives from gasoline was …

Effect of lead and cadmium to blood pressure on communities along coastal areas of Makassar, Indonesia

A Mallongi, AB Birawida, RDP Astuti, M Saleh - Enfermería Clínica, 2020 - Elsevier
Objectives This research aims to analyses the effect of lead and cadmium to the blood
pressure and the hypertension status among communities living along the coastal area of …

Influence of eNOS haplotypes on the plasma nitric oxide products concentrations in hypertensive and type 2 diabetes mellitus patients

VC Sandrim, RWC de Syllos, HRK Lisboa, GS Tres… - Nitric Oxide, 2007 - Elsevier
Endothelial nitric oxide synthase (eNOS) haplotypes are associated with hypertension (HT)
in patients with or without type 2 diabetes mellitus (T2DM). We evaluated the association of …

Long-term excessive selenium supplementation induces hypertension in rats

D Grotto, MFH Carneiro, MM De Castro… - Biological trace element …, 2018 - Springer
Selenium (Se) is an essential trace element involved in several biological pathways,
naturally found in rocks, soils, and food. Even though the daily requirement of Se is achieved …

Background values for essential and toxic elements in children's nails and correlation with hair levels

MFH Carneiro, D Grotto, BL Batista, CR Rhoden… - Biological trace element …, 2011 - Springer
Human nails are an attractive matrix for assessing environmental exposures to toxic
elements as well as the deficiency of essential elements since it is noninvasively collected …