Osteoarthritis (OA) is a complex disease characterized by cartilage degeneration and
persistent pain. Prostaglandin E2 (PGE2) plays a significant role in OA inflammation and …

Chronic pain begins with acute pain. Physicians tend to classify pain by duration (acute vs
chronic) and mechanism (nociceptive, neuropathic and nociplastic). Although this taxonomy …

Background Postoperative pain is common and may be severe. Postoperative
administration of non‐steroidal anti‐inflammatory drugs (NSAIDs) reduces patient opioid …

Objective. To evaluate the analgesic efficacy and safety of different does of intravenous
ibuprofen (IVIB) in the treatment of postoperative acute pain. Methods. Patients with an …

Background Children often require pain management following surgery to avoid suffering.
Effective pain management has consequences for healing time and quality of life. Ibuprofen …

This study aims to evaluate the efficacy and safety of multiple or single‐dosage intravenous
ibuprofen (IVIB) in managing postoperative pain and fever in adults who are unable to take …

Objectives: Interpret the epidemiology of ibuprofen toxicity when encountering patients in
clinical practice. Identify common history and physical examination findings in patients with …

Background/Objectives: Managing postoperative pain in patients with obesity is challenging.
Although using a combination of pain relief methods is recommended for these patients, the …

Injection of high-quality drugs can occasionally cause unexpected and unexplained local
complications. As the current standard for drug quality control does not include an …

Tramadol and codeine are both opioids used for pain control and management but are
prone to misuse and abuse despite the various side effects. This study, therefore, examined …