Administration of antioxidants in cancer: debate of the decade
Highlights•Concurrent administration of antioxidants in chemotherapy reduces efficacy of
treatment.•Administration of antioxidants should be in the form of a maintenance dose.•FDA …
treatment.•Administration of antioxidants should be in the form of a maintenance dose.•FDA …
Cyclodextrin modified erlotinib loaded PLGA nanoparticles for improved therapeutic efficacy against non-small cell lung cancer
This study was aimed at developing a nanoparticle strategy to overcome acquired
resistance against erlotinib in non-small cell lung cancer (NSCLC). To load erlotinib on …
resistance against erlotinib in non-small cell lung cancer (NSCLC). To load erlotinib on …
Potential of erlotinib cyclodextrin nanosponge complex to enhance solubility, dissolution rate, in vitro cytotoxicity and oral bioavailability
The present study was envisaged to evaluate the effect of erlotinib β-cyclodextrin
nanosponge (ERL-NS) on the solubility, dissolution, in vitro cytotoxicity and oral …
nanosponge (ERL-NS) on the solubility, dissolution, in vitro cytotoxicity and oral …
Antimicrobial and immunomodulatory efficacy of extracellularly synthesized silver and gold nanoparticles by a novel phosphate solubilizing fungus Bipolaris tetramera
Background Particulates of nanometers size have occupied a significant area in the field of
medicinal and agricultural purposes due to their large surface-to-volume ratio and …
medicinal and agricultural purposes due to their large surface-to-volume ratio and …
Bicontinuous cubic liquid crystalline nanoparticles for oral delivery of doxorubicin: implications on bioavailability, therapeutic efficacy, and cardiotoxicity
Purpose The present study explores the potential of bicontinous cubic liquid crystalline
nanoparticles (LCNPs) for improving therapeutic potential of doxorubicin. Methods …
nanoparticles (LCNPs) for improving therapeutic potential of doxorubicin. Methods …
Improved metabolic stability and therapeutic efficacy of a novel molecular gemcitabine phospholipid complex
The aim of the present research is to increase lipid solubility, metabolic stability and
therapeutic efficacy of water soluble gemcitabine (GEM) via phospholipid complex (PC) …
therapeutic efficacy of water soluble gemcitabine (GEM) via phospholipid complex (PC) …
Triple antioxidant SNEDDS formulation with enhanced oral bioavailability: Implication of chemoprevention of breast cancer
The present study aimed to develop quercetin, resveratrol and genistein loaded self-
nanoemulsifying drug delivery system (SNEDDS) by QbD approach in order to improve their …
nanoemulsifying drug delivery system (SNEDDS) by QbD approach in order to improve their …
Protein Nanoparticles for Enhanced Oral Delivery of Coenzyme-Q10: in Vitro and in Silico Studies
Coenzyme-Q10 (CoQ10) is a hydrophobic benzoquinone with antioxidant and anti-
inflammatory properties. It is known to reduce oxidative stress in various health conditions …
inflammatory properties. It is known to reduce oxidative stress in various health conditions …
Novel self-nanoemulsifying formulation of quercetin: Implications of pro-oxidant activity on the anticancer efficacy
The present work focuses on the anticancer potential of quercetin (QT) loaded self-
nanoemulsifying drug delivery system (QT-SNEDDS) composed of Capmul MCM, Tween 20 …
nanoemulsifying drug delivery system (QT-SNEDDS) composed of Capmul MCM, Tween 20 …
Biological evaluation of extracellular mycosynthesized silver nanoparticles by Trichoderma asperellum
Mycosynthesis of silver nano-scale particles by fungi is an important aspect in
nanotechnology due to its eco-friendly, safe, and cost-effective nature. It also provides …
nanotechnology due to its eco-friendly, safe, and cost-effective nature. It also provides …