Cerebral small vessel disease (cSVD) refers to the age-dependent pathological processes
involving the brain small vessels and leading to vascular cognitive impairment, intracerebral …

The high morbidity, mortality, and disability rates associated with cerebrovascular disease
(CeVD) pose a severe danger to human health. Gut bacteria significantly affect the onset …

Background: White matter hyperintensity (WMH) burden is associated with a higher risk of
ischemic stroke. Phenylacetylglutamine (PAGln) is a gut microbiota-derived metabolite that …

The gut microbiome interacts with the brain bidirectionally through the microbiome-gutbrain
axis, which plays a key role in regulating various nervous system pathophysiological …

Historically, females have been underrepresented in biological research. With increased
interest in the gut microbiome and the gut-brain axis, it is important for researchers to pursue …

Objectives: Short-chain fatty acids (SCFAs), the main metabolites released from the gut
microbiota, are altered during hypertension and obesity. SCFAs play a beneficial role in the …

Objective Previous studies have shown associations between the gut microbiota, microbial
metabolites, and cognitive decline. However, the effect of the dietary composition on such …

Background: Previous studies have demonstrated associations between gut microbiota,
microbial metabolites, and cognitive decline. However, relationships between these factors …

Stroke is the second most common cause of cognitive impairment and dementia. Vascular
dementia (VaD), a cognitive impairment following a stroke, is common and significantly …

There is increasing recognition of gut microbial dysbiosis in cerebral small vessel disease
(CSVD). The altered diversity in a single ecosystem-alpha diversity index of gut microbiota …